Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.86 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.86 |
| ▸ | MAPT | P10636 | 12/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394358 | 0.93 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPTTSHRMEN1 | |
| SCHEMBL31567888 | 0.88 | ALDH1A1 (0.81) | ALDH1A1HSD17B10MAPTTSHRMEN1 | |
| SCHEMBL18230644 | 0.87 | ALDH1A1 (0.80) | ALDH1A1HSD17B10MAPTTSHRMEN1 | |
| SCHEMBL31567862 | 0.87 | ALDH1A1 (0.80) | ALDH1A1HSD17B10MAPTTSHRMEN1 | |
| SCHEMBL31567873 | 0.86 | ALDH1A1 (0.78) | ALDH1A1HSD17B10MAPTTSHRMEN1 | |
| SCHEMBL8381158 | 0.86 | ALDH1A1 (0.78) | ALDH1A1HSD17B10MAPTTSHRMEN1 | |
| SCHEMBL8380625 | 0.86 | ALDH1A1 (0.78) | ALDH1A1HSD17B10MAPTTSHRMEN1 | |
| SCHEMBL31567857 | 0.86 | ALDH1A1 (0.78) | ALDH1A1HSD17B10MAPTTSHRMEN1 | |
| SCHEMBL31567878 | 0.84 | ALDH1A1 (0.74) | ALDH1A1HSD17B10MAPTTSHRMEN1 | |
| SCHEMBL8393774 | 0.83 | ALDH1A1 (0.60) | ALDH1A1HSD17B10MAPTTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777663-B1 | USE OF SUBSTITUTED 6-AMINO-4H-PYRANS | BAYER AG (DE) | 1999-05-26 | — | — | EP | claimed |
| US-5874462-A | Use of substituted 6-amino-4H-pyrans | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-23 | — | — | US | claimed |