Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791786 | 0.95 | KCNA3 (0.50) | ALDH1A1KMT2AMAPTMEN1KCNA3 | |
| SCHEMBL7786472 | 0.92 | KMT2A (0.52) | EGFRPIM1ALDH1A1KMT2AMAPT | |
| SCHEMBL7792089 | 0.91 | ALDH1A1 (0.49) | EGFRPIM1ALDH1A1KMT2AMAPT | |
| SCHEMBL8380843 | 0.91 | TTR (0.49) | ALDH1A1KMT2AMAPTMEN1KCNA3 | |
| SCHEMBL7795728 | 0.88 | KCNA3 (0.52) | ALDH1A1KCNA3MAOBKDM4ETDP1 | |
| SCHEMBL11604524 | 0.88 | KCNA3 (0.59) | ALDH1A1KMT2AMAPTMEN1KCNA3 | |
| SCHEMBL7786104 | 0.86 | KCNA3 (0.55) | ALDH1A1KMT2AMAPTMEN1KCNA3 | |
| Hydrochloric Acid SCHEMBL11604026 | 0.86 | KCNA3 (0.58) | ALDH1A1KMT2AMAPTMEN1KCNA3 | |
| SCHEMBL7795691 | 0.85 | ALDH1A1 (0.56) | EGFRPIM1ALDH1A1KMT2AMAPT | |
| SCHEMBL5745370 | 0.85 | KCNA3 (0.52) | EGFRALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-A1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997045397-A1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1997-12-04 | — | — | WO | disclosed |