Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | FAAH | O00519 | 6/20 | 0.54 |
| ▸ | F13A1 | P00488 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | TGM1 | P22735 | 1/20 | 0.54 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381166 | 0.89 | F13A1 (0.49) | MAPTFAAHF13A1TGM2TGM1 | |
| SCHEMBL8385674 | 0.86 | GLA (0.52) | MAPTFAAHF13A1TGM2TGM1 | |
| SCHEMBL7900109 | 0.85 | MAPT (0.49) | MAPTFAAHF13A1TGM2TGM1 | |
| SCHEMBL8381979 | 0.84 | MAPT (0.48) | MAPTFAAHF13A1TGM2TGM1 | |
| SCHEMBL8381216 | 0.82 | ST14 (0.45) | FAAHF13A1TGM2TGM1TGM3 | |
| SCHEMBL8381599 | 0.81 | ST14 (0.53) | F13A1TGM2TGM1TGM3POLB | |
| SCHEMBL8386390 | 0.80 | HTT (0.47) | F13A1TGM2TGM1TGM3POLB | |
| SCHEMBL8382214 | 0.80 | F13A1 (0.47) | MAPTF13A1TGM2TGM1TGM3 | |
| SCHEMBL13006300 | 0.80 | TMEM97 (0.57) | RAB9ANPC1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL12508855 | 0.79 | GRIN2B (0.67) | MAPTFAAHFOLH1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908843-A | Piperazine compounds as fibrinogen inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-06-01 | — | — | US | disclosed |