Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | F13A1 | P00488 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | TGM1 | P22735 | 1/20 | 0.47 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 4/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900109 | 0.95 | MAPT (0.49) | MAPTF13A1TGM2TGM1TGM3 | |
| SCHEMBL8385674 | 0.89 | GLA (0.52) | MAPTF13A1TGM2TGM1TGM3 | |
| SCHEMBL7909493 | 0.87 | F13A1 (0.44) | MAPTF13A1TGM2TGM1TGM3 | |
| SCHEMBL7906634 | 0.87 | MEN1 (0.49) | MAPTRAB9ANAMPTFAAHKDM4E | |
| SCHEMBL8382157 | 0.85 | HSP90AA1 (0.40) | F13A1TGM2TGM1TGM3HSP90AA1 | |
| Hydrochloric Acid SCHEMBL7909852 | 0.84 | POLB (0.51) | MAPTRAB9ANAMPTFAAHPOLB | |
| SCHEMBL8380994 | 0.84 | MAPT (0.58) | MAPTF13A1TGM2TGM1TGM3 | |
| SCHEMBL7906639 | 0.83 | MGLL (0.42) | MAPTRAB9ANAMPTFAAHPOLB | |
| SCHEMBL7907921 | 0.82 | ST14 (0.46) | F13A1TGM2TGM1TGM3FOLH1 | |
| SCHEMBL9415338 | 0.81 | ST14 (0.42) | F13A1TGM2TGM1TGM3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908843-A | Piperazine compounds as fibrinogen inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-06-01 | — | — | US | disclosed |