Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4389522 | 0.81 | ALDH1A1 (0.67) | CA12CA9ALDH1A1KDM4EHPGD | |
| SCHEMBL2762033 | 0.81 | EGLN1 (0.47) | — | |
| SCHEMBL27517970 | 0.78 | ALDH1A1 (0.53) | MCL1CA12CA9ESR2ALDH1A1 | |
| SCHEMBL17644468 | 0.77 | KDM4E (0.49) | MCL1CA12CA9ESR2ADORA3 | |
| SCHEMBL27517887 | 0.77 | ALDH1A1 (0.46) | CA12CA9ESR2ADORA3ADORA1 | |
| SCHEMBL27536538 | 0.77 | ESR2 (0.40) | MCL1CA12CA9ESR2ADORA3 | |
| SCHEMBL11491095 | 0.77 | ERAP1 (0.49) | MCL1ESR2ADORA3ADORA1ALDH1A1 | |
| SCHEMBL9842105 | 0.77 | MCL1 (0.56) | MCL1ESR2ADORA3ADORA1ALDH1A1 | |
| SCHEMBL8934515 | 0.77 | NQO1 (0.64) | MCL1ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL11395384 | 0.76 | ALDH1A1 (0.47) | MCL1ESR2ADORA3ADORA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308342-C | Ribose-substituted aromatic compounds, process for their preparation and their use as medicaments | AVENTIS PHARMA SA (FR) | 2007-04-04 | — | — | CN | disclosed |
| CN-1227564-A | Novel aromatic compounds substituted by ribose, preparation method and application as medicine thereof | HOECHST MARION ROUSSEL INC (FR) | 1999-09-01 | — | — | CN | disclosed |
| EP-0906326-A1 | NOVEL AROMATIC DERIVATIVES SUBSTITUTED BY A RIBOSE, THEIR METHOD OF PREPARATION AND APPLICATION AS MEDICINE | HOECHST MARION ROUSSEL (FR) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997047634-A1 | NOVEL AROMATIC DERIVATIVES SUBSTITUTED BY A RIBOSE, THEIR METHOD OF PREPARATION AND APPLICATION AS MEDICINE | HOECHST MARION ROUSSEL (FR) | 1997-12-18 | — | — | WO | disclosed |