Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381815 | 1.00 | PDPK1 (0.42) | PDPK1MTORSLC6A2BCHEACHE | |
| SCHEMBL22031145 | 0.83 | SLC6A2 (0.48) | PDPK1MTORSLC6A2BCHEACHE | |
| SCHEMBL5804981 | 0.83 | SLC6A2 (0.48) | PDPK1MTORSLC6A2BCHEACHE | |
| SCHEMBL22030353 | 0.83 | SLC6A2 (0.48) | PDPK1MTORSLC6A2BCHEACHE | |
| SCHEMBL7565013 | 0.83 | SLC6A2 (0.48) | PDPK1MTORSLC6A2BCHEACHE | |
| SCHEMBL26354181 | 0.82 | SLC6A2 (0.51) | PDPK1MTORSLC6A2BCHEACHE | |
| Bromide SCHEMBL7565722 | 0.82 | SLC6A2 (0.47) | PDPK1MTORSLC6A2BCHEACHE | |
| SCHEMBL23225625 | 0.81 | SLC6A2 (0.52) | PDPK1MTORSLC6A2BCHEACHE | |
| SCHEMBL8600114 | 0.80 | SLC6A2 (0.45) | PDPK1MTORSLC6A2BCHEACHE | |
| SCHEMBL7145503 | 0.80 | SLC6A2 (0.45) | PDPK1MTORSLC6A2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749976-B1 | ANTHRACYCLINE DERIVATIVES CONTAINING TRIFLUOROMETHYLATED SUGAR UNIT | ZAIDAN HOJIN BISEIBUTSU (JP) | 1999-04-28 | — | — | EP | disclosed |
| EP-0761678-B1 | Fluorine-containing anthracycline derivatives having hydroxyl group(s) mono- or di-o-aminoalkanoylated in the sugar moiety thereof | ZAIDAN HOJIN BISEIBUTSU (JP) | 1999-03-31 | — | — | EP | disclosed |
| US-5801257-A | DAUNOMYCIN ANTITUMOR | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1998-09-01 | — | — | US | disclosed |
| US-5789386-A | WATER SOLUBLE ANTITUMOR AGENTS; INJECTABLE | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1998-08-04 | — | — | US | disclosed |
| US-5719130-A | HIGH ANTITUMOR ACTIVITY, LOWER TOXICITY | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0761678-A1 | Fluorine-containing anthracycline derivatives having hydroxyl group(s) mono- or di-o-aminoalkanoylated in the sugar moiety thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1997-03-12 | — | — | EP | disclosed |
| EP-0749976-A1 | NOVEL ANTHRACYCLINE DERIVATIVES CONTAINING TRIFLUOROMETHYLATED SUGAR UNIT | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1996-12-27 | — | — | EP | disclosed |