Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 7/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378813 | 0.95 | EGLN1 (0.38) | EGLN1F10TPSAB1LMNAKLKB1 | |
| SCHEMBL8382712 | 0.88 | EGLN1 (0.39) | EGLN1F10TPSAB1KLKB1F2 | |
| SCHEMBL8382987 | 0.86 | F10 (0.38) | EGLN1F10TPSAB1KLKB1F2 | |
| SCHEMBL8382018 | 0.79 | HDAC6 (0.35) | EGLN1F10LMNAKLKB1F2 | |
| SCHEMBL8380898 | 0.76 | SLC6A7 (0.43) | F10TSHR | |
| SCHEMBL27412209 | 0.75 | GLA (0.40) | EGLN1GAATSHRPOLB | |
| SCHEMBL27476670 | 0.73 | SCN9A (0.40) | EGLN1RAB9ATSHR | |
| SCHEMBL9078301 | 0.72 | CSNK2A1 (0.35) | EGLN1F10F2F7F3 | |
| SCHEMBL7014454 | 0.71 | F10 (0.34) | EGLN1F10F2F7F3 | |
| SCHEMBL7013669 | 0.70 | F10 (0.38) | F10LMNAF2F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889009-A | ADMINISTERING 1,7-DISUBSTITUTED-4-OX-3-(QUINOLINECARBOXYLIC ACID OR NAPHTHYRIDINECARBOXYLIC ACID) | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-30 | — | — | US | disclosed |
| US-5703081-A | CELL ADHESION INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-30 | — | — | US | disclosed |