SCHEMBL838277

SCHEMBL838277

CCC(C)[Si](O)(O)C(C)CC

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14247816 0.84 TSHR (0.30) TSHR
SCHEMBL618550 0.79 TSHR (0.41) TSHR
SCHEMBL838569 0.79
SCHEMBL18014660 0.76
SCHEMBL8903049 0.76
SCHEMBL2027025 0.76 TSHR (0.39) TSHR
SCHEMBL2014560 0.73 TSHR (0.37) TSHR
SCHEMBL837006 0.73 TSHR (0.41) TSHR
SCHEMBL2022165 0.73 TSHR (0.37) TSHR
SCHEMBL14749893 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140249326-A1 Method of Synthesizing Siloxane Monomers and Use Thereof SILECS OY (FI) 2014-09-04 US claimed
US-20250313752-A1 METHOD FOR PRODUCING AQUEOUS SOLUTION OF PURIFIED AMINOSILANOL COMPOUND AND AMINOSILOXANE COMPOUND, AND COMPOSITION FOR ETCHING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-10-09 US disclosed
EP-4527841-A1 METHOD FOR PRODUCING AQUEOUS SOLUTION OF PURIFIED AMINOSILANOL COMPOUND AND AMINOSILOXANE COMPOUND, AND COMPOSITION FOR ETCHING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-03-26 EP disclosed
WO-2023223803-A1 METHOD FOR PRODUCING AQUEOUS SOLUTION OF PURIFIED AMINOSILANOL COMPOUND AND AMINOSILOXANE COMPOUND, AND COMPOSITION FOR ETCHING 信越化学工業株式会社 2023-11-23 WO disclosed
US-9458183-B2 Method of synthesizing siloxane monomers and use thereof SILECS OY (FI) 2016-10-04 US disclosed
US-20140249326-A1 Method of Synthesizing Siloxane Monomers and Use Thereof SILECS OY (FI) 2014-09-04 US disclosed
EP-1904415-B1 HYDROPHOBING MINERALS AND FILLER MATERIALS DOW CORNING (US) 2014-03-12 EP disclosed
US-8142856-B2 Preparing hydrolyzate containing polysiloxanes by hydrolyzing hydrolysable silane or hydrolysable silane mixture in presence of acid hydrolysis catalyst andcombining polysiloxane hydrolyzate with mineral and/or filler and optionally with water and/or a catalyst for condensation of the hydrolyzate DOW CORNING CORPORATION (US) 2012-03-27 US disclosed
US-7932330-B2 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-26 US disclosed
US-7592402-B2 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-09-22 US disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed
US-5106959-A Intermediates for ceramics, gels, films, optical fibers, polymerization catalysts and silicone curing agents RHONE-POULENC, INC. (US) 1992-04-21 US disclosed
US-5099006-A ompounds for use in paints, for waterproofing, as adhesion promoters, mordants, sizing agents and intermediates RHONE-POULENC INC. (US) 1992-03-24 US disclosed
US-5017695-A With cerium ammonium nitrate and silanol-type compound RHONE-POULENC, INC. (US) 1991-05-21 US disclosed
US-5017694-A With silanol-type compounds RHONE-POULENC, INC. (US) 1991-05-21 US disclosed
EP-0324671-A2 Alkoxy-type derivatives of trivalent metals of group 3b, and their preparation RHONE-POULENC CHIMIE (FR) 1989-07-19 EP disclosed
EP-0319383-A2 Process for the fabrication of cerium hydrocarbonsilyloxides by transetherification of cerium alkoxides RHONE-POULENC CHIMIE (FR) 1989-06-07 EP disclosed
EP-0319384-A2 Cerium hydrocarbonsilyloxydes and process for their manufacture RHONE-POULENC CHIMIE (FR) 1989-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140249326-A1 Method of Synthesizing Siloxane Monomers and Use Thereof MSMO1, PCNA, PIEZO1 TSHR 4868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.