Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.46 |
| ▸ | DRD3 | P35462 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383518 | 0.90 | DRD2 (0.47) | DRD2DRD3NPC1MTORRAB9A | |
| SCHEMBL8386603 | 0.89 | DRD2 (0.41) | DRD2DRD3NPC1MTORRAB9A | |
| SCHEMBL8385726 | 0.89 | NPC1 (0.48) | DRD2DRD3NPC1MTORRAB9A | |
| SCHEMBL8382233 | 0.89 | NPC1 (0.48) | DRD2DRD3NPC1MTORRAB9A | |
| SCHEMBL8383265 | 0.89 | NPC1 (0.48) | DRD2DRD3NPC1MTORRAB9A | |
| SCHEMBL8383173 | 0.89 | NPC1 (0.48) | DRD2DRD3NPC1MTORRAB9A | |
| SCHEMBL8385737 | 0.88 | CYP1A2 (0.49) | DRD2DRD3NPC1MTORRAB9A | |
| SCHEMBL8381968 | 0.88 | CYP1A2 (0.49) | DRD2DRD3NPC1MTORRAB9A | |
| SCHEMBL8315948 | 0.87 | DRD2 (0.46) | DRD2DRD3NPC1MTORRAB9A | |
| SCHEMBL8314614 | 0.86 | DRD2 (0.49) | DRD2DRD3NPC1MTORRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891882-A | TREATING BENIGN PROSTATIC HYPERPLASIA OR OTHER UROLOGICAL DISEASES SUCH AS BLADDER OUTLET OBSTRUCTION AND NEUROGENIC BLADDER, OR GYNECOLOGICAL SYNDROMES SUCH AS DYSMENORRHEA | ABBOTT LABORATORIES (US) | 1999-04-06 | — | — | US | disclosed |