Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 12/20 | 0.48 |
| ▸ | NPC1 | O15118 | 11/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285835 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9ANPC1CDK5CDK5R1 | |
| SCHEMBL28093052 | 0.80 | CES1 (0.38) | SMN1; SMN2RAB9ANPC1L3MBTL1PKM | |
| Trifluoroacetic Acid SCHEMBL7281971 | 0.78 | NPC1 (0.43) | SMN1; SMN2RAB9ANPC1CDK5CDK5R1 | |
| Trifluoroacetic Acid SCHEMBL8383199 | 0.78 | NPC1 (0.43) | SMN1; SMN2RAB9ANPC1CDK5CDK5R1 | |
| SCHEMBL8377878 | 0.76 | TNF (0.50) | SMN1; SMN2RAB9ANPC1CDK5CDK5R1 | |
| SCHEMBL31628121 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1L3MBTL1PKM | |
| SCHEMBL7286411 | 0.73 | HPGD (0.39) | SMN1; SMN2RAB9ANPC1L3MBTL1PKM | |
| SCHEMBL8370038 | 0.73 | TSHR (0.48) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL2455339 | 0.72 | NPC1 (0.49) | SMN1; SMN2RAB9ANPC1L3MBTL1PKM | |
| SCHEMBL21177990 | 0.71 | KMT2A (0.39) | RAB9ANPC1ATMPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5973188-A | Acetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-10-26 | — | — | US | disclosed |
| US-5726185-A | BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |