Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2234094 | 0.85 | KMT2A (0.71) | KMT2APARP10CA1CA2MAPK1 | |
| SCHEMBL29088631 | 0.84 | ELANE (0.57) | KMT2APARP10POLBSRD5A2CYP1A2 | |
| SCHEMBL7395765 | 0.84 | KMT2A (0.65) | KMT2APARP10CA1CA2PARP15 | |
| SCHEMBL1328578 | 0.82 | GAA (0.56) | KMT2APARP10POLBCYP1A2GAA | |
| SCHEMBL8613306 | 0.81 | PARP10 (0.48) | KMT2APARP10CA1CA2POLB | |
| SCHEMBL7074553 | 0.81 | KMT2A (0.54) | KMT2APARP10POLBCYP1A2GAA | |
| SCHEMBL7074556 | 0.81 | KMT2A (0.54) | KMT2APARP10POLBCYP1A2GAA | |
| SCHEMBL8612180 | 0.81 | PARP10 (0.48) | KMT2APARP10CA1CA2POLB | |
| SCHEMBL15652500 | 0.81 | PARP10 (0.48) | KMT2APARP10MAPK1POLBCYP1A2 | |
| SCHEMBL31147135 | 0.81 | PARP10 (0.48) | KMT2APARP10MAPK1POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703216-B1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0703216-A1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-03-27 | — | — | EP | disclosed |