Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074556 | 1.00 | KMT2A (0.54) | KMT2AMEN1PARP10ALDH1A1CYP1A2 | |
| SCHEMBL31147135 | 0.84 | PARP10 (0.48) | KMT2APARP10ALDH1A1CYP1A2GAA | |
| SCHEMBL8613306 | 0.84 | PARP10 (0.48) | KMT2APARP10ALDH1A1CYP1A2GAA | |
| SCHEMBL8613307 | 0.84 | PARP10 (0.48) | KMT2APARP10ALDH1A1CYP1A2GAA | |
| SCHEMBL15652500 | 0.84 | PARP10 (0.48) | KMT2APARP10ALDH1A1CYP1A2GAA | |
| SCHEMBL8612180 | 0.84 | PARP10 (0.48) | KMT2APARP10ALDH1A1CYP1A2GAA | |
| SCHEMBL1117012 | 0.84 | TAS1R3 (0.65) | KMT2AMEN1PARP10ALDH1A1GAA | |
| SCHEMBL4689279 | 0.82 | POLB (0.62) | KMT2AMEN1PARP10ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL31147134 | 0.82 | PARP10 (0.47) | KMT2APARP10ALDH1A1CYP1A2GAA | |
| SCHEMBL6479499 | 0.82 | ALDH1A1 (0.55) | KMT2AMEN1PARP10ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059356-A2 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |