SCHEMBL838414

SCHEMBL838414

Cc1cccnc1NN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31251527 1.00
Hydrochloric Acid SCHEMBL23235050 0.98 L3MBTL1 (0.56)
SCHEMBL15368480 0.81 NPC1 (0.61)
SCHEMBL30671581 0.79
SCHEMBL292777 0.79
SCHEMBL2400485 0.77
SCHEMBL10616328 0.77
SCHEMBL25775968 0.77
SCHEMBL1223336 0.77
SCHEMBL31026295 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118955469-A Pyrazole alcohol compound as well as preparation method and application thereof 安徽中医药大学 2024-11-15 CN claimed
CN-119264054-B Pyrazolecarboxylic acid borneol ester compound and preparation method and application thereof 安徽中医药大学 2025-04-01 CN disclosed
CN-119264054-A Pyrazolecarboxylic acid borneol ester compound and preparation method and application thereof 安徽中医药大学 2025-01-07 CN disclosed
CN-118955469-A Pyrazole alcohol compound as well as preparation method and application thereof 安徽中医药大学 2024-11-15 CN disclosed
CN-118184681-A Spiro 1,2, 4-triazole carbene metal complex, intermediate, preparation method and application thereof 浙江工业大学 2024-06-14 CN disclosed
EP-3807266-B1 PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2023-10-25 EP disclosed
EP-3807266-B1 PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2023-10-25 EP disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
WO-2023076586-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. (US) 2023-05-04 WO disclosed
CN-112585128-B Pyrazole derivatives as MALT1 inhibitors 詹森药业有限公司 2023-02-21 CN disclosed
US-5750550-A RESPIRATORY SYSTEM DISORDERS SANOFI (FR) 1998-05-12 US disclosed
WO-1997010243-A1 2-(PYRAZOL-5-YL-OXYMETHYL)-1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SANOFI (US) 1997-03-20 WO disclosed
EP-0366328-B1 PROCESS FOR PREPARING 4-METHYLPYRAZOLES NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1993-05-19 EP disclosed
US-5141855-A Forming cobalt complex of metallizable dye; analyte as reductant or producing reductant; spectrophotometric analysis of enzymes, blood, urine EASTMAN KODAK COMPANY (US) 1992-08-25 US disclosed
EP-0441718-A1 Herbicidally active triazolopyridine compounds RHONE-POULENC AGROCHIMIE (FR) 1991-08-14 EP disclosed
CN-1053792-A Herbicidal compound with triazolopyridine group RHONE POULENO AGROCHIMIE (FR) 1991-08-14 CN disclosed
US-4986934-A SPIROBENZOXAZINE PYRROLOPYRIDINE COMPOUNDS, EYEGLASSES PPG INDUSTRIES, INC. (US) 1991-01-22 US disclosed
EP-0366328-A1 Process for preparing 4-methylpyrazoles NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1990-05-02 EP disclosed
EP-0255089-A2 Cobalt containing reagents and methods for the determination of analytes in aqueous fluids EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-02-03 EP disclosed
US-4293553-A ANTITHROMBOTIC AGENT Ishikawa, Masayuki (JP) 1981-10-06 US disclosed