SCHEMBL8384148

SCHEMBL8384148

Cc1ccc([SiH](C)[SiH3])cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.47
TDP1 Q9NUW8 1/20 0.47
ALDH1A1 P00352 5/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 3/20 0.33
LMNA P02545 2/20 0.33
ALOX12 P18054 1/20 0.33
NFE2L2 Q16236 1/20 0.33
SRD5A2 P31213 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
CYP2A6 P11509 2/20 0.32
IDO1 P14902 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8385106 0.79 ACHE (0.50) ACHETDP1ALDH1A1CA1CA2
SCHEMBL8384038 0.78 ACHE (0.42) ACHETDP1ALDH1A1CA1CA2
SCHEMBL476102 0.75 ACHE (0.53) ACHETDP1ALDH1A1CA1CA2
SCHEMBL8385547 0.75 ACHE (0.53) ACHETDP1ALDH1A1CA1CA2
SCHEMBL1049035 0.75 ACHE (0.53) ACHETDP1ALDH1A1CA1CA2
SCHEMBL8380718 0.73
SCHEMBL126082 0.71 ACHE (0.57) ACHETDP1ALDH1A1CA1CA2
SCHEMBL24624090 0.71 ACHE (0.47) ACHETDP1ALDH1A1CA1CA2
SCHEMBL8382290 0.71 ACHE (0.47) ACHETDP1ALDH1A1CA1CA2
SCHEMBL18798568 0.71 ACHE (0.47) ACHETDP1ALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0630933-B1 A method of producing a semiconducting material NIPPON OIL CO LTD (JP) 1999-04-14 EP disclosed
US-5700400-A Method for producing a semiconducting material NIPPON OIL CO., LTD. (JP) 1997-12-23 US disclosed
EP-0551771-B1 Process for producing polysilanes NIPPON OIL CO LTD (JP) 1997-07-30 EP disclosed
US-5620531-A Photovoltaic element NIPPON OIL CO., LTD. (JP) 1997-04-15 US disclosed
EP-0717451-A2 Photovoltaic element NIPPON OIL CO., LTD. (JP) 1996-06-19 EP disclosed
EP-0630933-A2 A method of producing a semiconducting material NIPPON OIL CO. LTD. (JP) 1994-12-28 EP disclosed
US-5304622-A Process for producing polysilanes NIPPON OIL COMPANY, LTD. (JP) 1994-04-19 US disclosed
EP-0551771-A2 Process for producing polysilanes NIPPON OIL CO. LTD. (JP) 1993-07-21 EP disclosed