Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.76 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.76 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.76 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.76 |
| ▸ | DGKA | P23743 | 1/20 | 0.67 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8384458 | 1.00 | PRKCA (0.76) | PRKCAPRKCEPRKCQPRKCDDGKA | |
| SCHEMBL23743700 | 0.93 | PRKCA (0.69) | PRKCAPRKCEPRKCQPRKCDDGKA | |
| SCHEMBL25774242 | 0.93 | PRKCA (0.70) | PRKCAPRKCEPRKCQPRKCDDGKA | |
| SCHEMBL8036933 | 0.93 | PRKCA (0.70) | PRKCAPRKCEPRKCQPRKCDDGKA | |
| SCHEMBL8049125 | 0.93 | PRKCA (0.70) | PRKCAPRKCEPRKCQPRKCDDGKA | |
| SCHEMBL8389636 | 0.92 | PRKCA (0.68) | PRKCAPRKCEPRKCQPRKCDDGKA | |
| SCHEMBL24474059 | 0.90 | PRKCA (0.64) | PRKCAPRKCEPRKCQPRKCDDGKA | |
| SCHEMBL528434 | 0.88 | PRKCA (0.82) | PRKCAPRKCEPRKCQPRKCDDGKA | |
| SCHEMBL24219862 | 0.88 | PRKCE (0.62) | PRKCAPRKCEPRKCQPRKCDDGKA | |
| SCHEMBL10426842 | 0.87 | PRKCA (0.75) | PRKCAPRKCEPRKCQPRKCDDGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655907-B1 | USE OF DIACYLOLYCEROLS FOR INCREASING THE MELANIN CONTENT IN MELANOCYTES | UNIV BOSTON (US) | 1999-04-28 | — | — | EP | claimed |
| WO-1996009810-A1 | METHODS FOR ENHANCING MELANIN SYNTHESIS IN MELANOCYTES USING DIACYLGLYCEROLS AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 1996-04-04 | — | — | WO | claimed |
| EP-0655907-B1 | USE OF DIACYLOLYCEROLS FOR INCREASING THE MELANIN CONTENT IN MELANOCYTES | UNIV BOSTON (US) | 1999-04-28 | — | — | EP | disclosed |
| US-5750091-A | Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof | THE TRUSTEES OF BOSTON UNIVERSITY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5700450-A | Methods for enhancing melanin synthesis in melanocytes using diacyglycerols and uses thereof | THE TRUSTEES OF BOSTON UNIVERSITY (US) | 1997-12-23 | — | — | US | disclosed |
| US-5352440-A | Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof | TRUSTEES OF BOSTON UNIVERSITY (US) | 1994-10-04 | — | — | US | disclosed |
| EP-0373195-A1 | COMPOSITION FOR INCREASING MELANIN CONTENT OF MELANOCYTES IN-VIVO AND IN-VITRO AND METHODS FOR THE IN-VITRO USE THEREOF. | TUFTS COLLEGE (US) | 1990-06-20 | — | — | EP | disclosed |
| EP-0373195-A4 | COMPOSITION FOR INCREASING MELANIN CONTENT OF MELANOCYTES IN-VIVO AND IN-VITRO AND METHODS FOR THE IN-VITRO USE THEREOF. | TUFTS COLLEGE (US) | 1990-05-14 | — | — | EP | disclosed |
| WO-1989009258-A1 | METHODS FOR INCREASING MELANIN CONTENT AND FOR INDUCING MELANOCYTE PROLIFERATION IN-VIVO AND IN-VITRO | TRUSTEES OF TUFTS COLLEGE (US) | 1989-10-05 | — | — | WO | disclosed |