SCHEMBL8384606

SCHEMBL8384606

Oc1ccc(P(O)O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.53
ALDH1A1 P00352 3/20 0.53
CA3 P07451 3/20 0.53
CA14 Q9ULX7 3/20 0.53
CYP3A4 P08684 2/20 0.53
HIF1A Q16665 2/20 0.53
HSD17B10 Q99714 2/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
KDM4E B2RXH2 2/20 0.53
MAPT P10636 2/20 0.53
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA4 P22748 2/20 0.53
CA9 Q16790 2/20 0.53
NPC1 O15118 1/20 0.53
GMNN O75496 1/20 0.53
LMNA P02545 1/20 0.53
TYR P14679 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9818511 0.86 ESR1 (0.32) ESR1ESR2
Hydroquinone SCHEMBL9312654 0.78
SCHEMBL3833957 0.76 ESR1 (0.78) ALOX15ALDH1A1CA3CA14CYP3A4
SCHEMBL4434791 0.76 ESR1 (0.39) ALDH1A1CYP3A4ESR1ESR2L3MBTL1
Bromide SCHEMBL10792390 0.73 ESR1 (0.74) ALOX15ALDH1A1CA3CA14CYP3A4
Hydroquinone SCHEMBL11511669 0.73 ALOX15 (1.00) ALOX15ALDH1A1CA3CA14CYP3A4
Hydroquinone SCHEMBL460669 0.73 ALOX15 (1.00) ALOX15ALDH1A1CA3CA14CYP3A4
Hydroquinone SCHEMBL15516 0.73
SCHEMBL5605918 0.71 ESR1 (0.56) ALOX15ALDH1A1CA3CA14CYP3A4
SCHEMBL11770595 0.71 CYP2A6 (0.50) ALOX15ALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487343-B1 Process for preparing a lithographic plate FUJI PHOTO FILM CO LTD (JP) 1999-04-28 EP disclosed
EP-0487343-A1 Process for preparing a lithographic plate Fuji Photo Film Co., Ltd. (JP) 1992-05-27 EP disclosed