SCHEMBL8385

SCHEMBL8385

O=[C]c1ccccc1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
ALOX15 P16050 1/20 0.59
CA12 O43570 3/20 0.50
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA4 P22748 3/20 0.50
CA7 P43166 3/20 0.50
CA9 Q16790 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 1/20 0.50
HMGB1 P09429 1/20 0.50
HPGD P15428 1/20 0.50
CA6 P23280 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
CA14 Q9ULX7 1/20 0.50
MAPT P10636 2/20 0.48
HDAC8 Q9BY41 1/20 0.48
POLB P06746 1/20 0.46
AKR1C3 P42330 1/20 0.46
NR4A1 P22736 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28107215 0.92 ALDH1A1 (0.50) ALDH1A1ALOX15CA12CA1CA2
SCHEMBL69321 0.83 ALDH1A1 (0.62) ALDH1A1ALOX15CA12CA1CA2
SCHEMBL29409566 0.83 ALDH1A1 (0.62) ALDH1A1ALOX15CA12CA1CA2
SCHEMBL9854738 0.83 ALDH1A1 (0.50) ALDH1A1ALOX15CA12CA1CA2
SCHEMBL1157075 0.81 ALDH1A1 (0.40) ALDH1A1ALOX15CA12CA1CA2
SCHEMBL7178852 0.80 ALDH1A1 (0.53) ALDH1A1ALOX15CA12CA1CA2
SCHEMBL5858945 0.80 ALDH1A1 (0.46) ALDH1A1ALOX15CA12CA1CA2
SCHEMBL11730084 0.80 ALDH1A1 (0.46) ALDH1A1ALOX15CA12CA1CA2
SCHEMBL64069 0.80 AKR1C3 (0.57) ALDH1A1CA12CA1CA2CA4
SCHEMBL1331831 0.80 AKR1C3 (0.57) ALDH1A1CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12136 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240190809-A1 THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS AWAKN LS EUROPE HOLDINGS LIMITED (IE) 2024-06-13 US claimed
CN-118019451-A Fungicidal compositions comprising fludioxonil 先正达农作物保护股份公司 2024-05-10 CN claimed
CN-115368331-B Dihydro-pyrone compound and preparation method and application thereof 复旦大学 2024-04-30 CN claimed
EP-4337316-A1 THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS Awakn Ls Europe Holdings Limited (IE) 2024-03-20 EP claimed
CN-117500802-A LACTIVICIN compounds, their preparation and their use as antibacterial agents 费多拉制药有限公司 2024-02-02 CN claimed
WO-2023241618-A1 AMINOPYRIMIDINE COMPOUNDS AND USE THEREOF 南京明德新药研发有限公司 2023-12-21 WO claimed
US-20230346879-A1 COMPOSITIONS AND METHODS FOR COMBINATORIAL DRUG DISCOVERY IN NANOLITER DROPLETS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2023-11-02 US claimed
WO-2023154852-A1 ANTIBODY BARCODED BEADS AND USES THEREOF CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-08-17 WO claimed
US-11707530-B2 Ligand capable of multivalently binding to glutamine transporter, and composition comprising same TOKYO INSTITUTE OF TECHNOLOGY (JP) 2023-07-25 US claimed
WO-2023137387-A2 TETRAHEDRAL ANTIBODIES BIOMOLECULAR HOLDINGS LLC (US) 2023-07-20 WO claimed
US-4053486-A STEREOSPECIFIC TOTAL STEROIDAL SYNTHESIS VIA SUBSTITUTED C/D-TRANS INDANONES HOFFMANN-LA ROCHE INC. (US) 1977-10-11 US claimed
US-4048195-A Process of synthesizing substituted indanones HOFFMANN-LA ROCHE INC. (US) 1977-09-13 US claimed
US-4012345-A POLYPEPTIDES WHICH INHIBIT SECRETION OF GROWTH HORMONE SOMATOTROPIN AMERICAN HOME PRODUCTS CORPORATION (US) 1977-03-15 US claimed
US-3997517-A PEPTIDE AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-14 US claimed
US-3985733-A Stereospecific total steroidal synthesis via substituted C/D-trans indanones HOFFMANN-LA ROCHE INC. (US) 1976-10-12 US claimed
US-3984417-A Method of producing active amino acid esters AJINOMOTO CO., INC. (JA) 1976-10-05 US claimed
US-3953596-A 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals ICI UNITED STATES INC. (US) 1976-04-27 US claimed
US-3951964-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-04-20 US claimed
US-3933783-A Formation of peptide bonds in the presence of isonitriles AJINOMOTO CO., INC. (JA) 1976-01-20 US claimed
US-3933849-A INDICATOR DYES AS OPTICAL FILTER AGENTS POLAROID CORPORATION (US) 1976-01-20 US claimed