Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25353994 | 0.68 | KMT2A (0.43) | MAOAMAOBMAPK1ALDH1A1KDM4E | |
| SCHEMBL4748476 | 0.66 | ALDH1A1 (0.52) | NTRK1PIM1ACVR1CYP11B1CYP11B2 | |
| SCHEMBL11752921 | 0.65 | ALDH1A1 (0.50) | NTRK1PIM1ACVR1CYP11B1CYP11B2 | |
| SCHEMBL17754184 | 0.63 | ALDH1A1 (0.43) | NTRK1PIM1ACVR1CYP11B1CYP11B2 | |
| SCHEMBL11751395 | 0.63 | ALDH1A1 (0.43) | NTRK1PIM1ACVR1CYP11B1CYP11B2 | |
| SCHEMBL21611244 | 0.62 | CYP1A2 (0.35) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20075887 | 0.62 | GSK3B (0.48) | MAPK1MEN1KMT2AIDO1FLT3 | |
| SCHEMBL17795213 | 0.62 | TNF (0.48) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14394534 | 0.61 | NPC1 (0.44) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15355017 | 0.61 | NPC1 (0.45) | NTRK1PIM1ACVR1PTGS2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869683-A | Processes for producing 1-substituted-2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0705823-A1 | Process for producing 1-substituted-2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1996-04-10 | — | — | EP | disclosed |