Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.75 |
| ▸ | GSK3B | P49841 | 2/20 | 0.64 |
| ▸ | KDM1A | O60341 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | TNF | P01375 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TACR2 | P21452 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28884409 | 1.00 | IDO1 (0.75) | IDO1GSK3BKDM1AKMT2AMEN1 | |
| SCHEMBL837806 | 0.99 | IDO1 (0.73) | IDO1GSK3BKDM1AKMT2AMEN1 | |
| Potassium SCHEMBL837807 | 0.99 | IDO1 (0.73) | IDO1GSK3BKDM1AKMT2AMEN1 | |
| SCHEMBL17867048 | 0.89 | IDO1 (0.76) | IDO1GSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL2042419 | 0.89 | IDO1 (0.76) | IDO1GSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL12809540 | 0.89 | IDO1 (0.76) | IDO1GSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL14595068 | 0.89 | IDO1 (0.76) | IDO1GSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL13399673 | 0.89 | IDO1 (0.76) | IDO1GSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL25366253 | 0.86 | IDO1 (1.00) | IDO1GSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL838583 | 0.86 | IDO1 (1.00) | IDO1GSK3BKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114686464-A | Application of D-N-carbamyl hydrolase in production of D-tryptophan | 湖南引航生物科技有限公司 | 2022-07-01 | — | — | CN | claimed |
| US-9957536-B2 | Mutants of hydantoinase | EVONIK TECHNOCHEMIE GMBH (DE) | 2018-05-01 | — | — | US | claimed |
| EP-2780451-B1 | MUTANTS OF HYDANTOINASE | EVONIK TECHNOCHEMIE GMBH (DE) | 2017-09-20 | — | — | EP | claimed |
| US-20150056667-A1 | MUTANTS OF HYDANTOINASE | EVONIK OPERATIONS GMBH (DE) | 2015-02-26 | — | — | US | claimed |
| EP-2780451-A1 | MUTANTS OF HYDANTOINASE | Evonik Industries AG (DE) | 2014-09-24 | — | — | EP | claimed |
| WO-2013072486-A1 | MUTANTS OF HYDANTOINASE | EVONIK INDUSTRIES AG (DE) | 2013-05-23 | — | — | WO | claimed |
| EP-1666588-B1 | NOVEL TRANSPORTER PROTEIN | AJINOMOTO KK (JP) | 2011-05-11 | — | — | EP | claimed |
| US-5338859-A | Reacting a hydantoin with a calcium base; crystallization; precipitation; separation | HOECHST CELANESE CORPORATION (US) | 1994-08-16 | — | — | US | claimed |
| US-4436910-A | SAPONIFICATION | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-03-13 | — | — | US | claimed |
| US-4082767-A | CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-04-04 | — | — | US | claimed |
| US-4016037-A | FERMENTING A HYDANTOIN COMPOUND WITH FLAVOBACTERIUM AMINOGENES OR ITS ENZYMES | AJINOMOTO CO., INC. (JA) | 1977-04-05 | — | — | US | claimed |
| JP-59013779-A | — | — | None | — | — | JP | disclosed |
| JP-59156293-A | — | — | None | — | — | JP | disclosed |
| CN-114686464-B | Application of D-N-carbamyl hydrolase in production of D-tryptophan | 湖南引航生物科技有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-115772513-A | D-carbamyl hydrolase mutant, gene, expression vector and application thereof | 江南大学 | 2023-03-10 | — | — | CN | disclosed |
| US-4436910-A | SAPONIFICATION | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-03-13 | — | — | US | disclosed |
| JP-S5913779-A | PREPARATION OF 3,6-BIS(INDOLE-3-YLMETHYL)2,5-PIPERAZINEDIONE | SUMITOMO CHEM CO LTD | 1984-01-24 | — | — | JP | disclosed |
| US-4110536-A | ANTIARRHYTHMIA | MILES LABORATORIES, INC. (US) | 1978-08-29 | — | — | US | disclosed |
| US-4082767-A | CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-04-04 | — | — | US | disclosed |
| US-4016037-A | FERMENTING A HYDANTOIN COMPOUND WITH FLAVOBACTERIUM AMINOGENES OR ITS ENZYMES | AJINOMOTO CO., INC. (JA) | 1977-04-05 | — | — | US | disclosed |