SCHEMBL8385273

SCHEMBL8385273

C=C(COC(=O)c1ccc(O)cc1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.60
ESR2 Q92731 4/20 0.55
ESR1 P03372 3/20 0.55
ALDH1A1 P00352 3/20 0.53
KDM4E B2RXH2 2/20 0.53
GAA P10253 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
MAPK1 P28482 1/20 0.53
KMT2A Q03164 2/20 0.51
SLC6A2 P23975 1/20 0.51
SLC6A3 Q01959 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
MEN1 O00255 1/20 0.51
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA7 P43166 1/20 0.51
CA9 Q16790 1/20 0.51
CA14 Q9ULX7 1/20 0.51
RAB9A P51151 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5143592 0.91 TDP1 (0.57) LMNAESR2ESR1ALDH1A1KDM4E
SCHEMBL5152874 0.80 ESR1 (0.80) LMNAESR2ESR1ALDH1A1MAPK1
SCHEMBL5157212 0.80 LMNA (0.70) LMNAESR2ESR1ALDH1A1KDM4E
SCHEMBL9417086 0.79 LMNA (0.59) LMNAESR2ESR1ALDH1A1KDM4E
SCHEMBL14457923 0.78 TDP1 (0.59) LMNAESR2ESR1ALDH1A1KDM4E
SCHEMBL831507 0.78 LMNA (0.62) LMNAESR2ESR1ALDH1A1KDM4E
SCHEMBL17231742 0.77 MAPK1 (0.62) LMNAESR2ESR1ALDH1A1KDM4E
SCHEMBL5153066 0.77 TDP1 (0.81) LMNAESR2ESR1ALDH1A1MAPK1
SCHEMBL5152566 0.77 TDP1 (0.75) LMNAESR2ESR1ALDH1A1MAPK1
SCHEMBL14045405 0.76 ESR2 (0.52) LMNAESR2ESR1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001932-A ACRYLIC ESTER COPOLYMER WITH VINYL ETHER, VINYL ESTER COPOLYMERS FOR RUBBER BLENDS NIPPON MEKTRON, LIMITED (JP) 1999-12-14 US disclosed
EP-0761702-B1 Novel acrylic copolymer elastomer, its blend rubber and blend rubber composition NIPPON MEKTRON KK (JP) 1999-10-27 EP disclosed
EP-0755952-B1 Acrylic copolymer elastomer, its blend rubber and blend rubber composition NIPPON MEKTRON KK (JP) 1999-10-20 EP disclosed
US-5959037-A IMPROVED COLD RESISTANCE AND AN INTERMEDIATE HEAT RESISTANCE BETWEEN THE HEAT RESISTANCE OF ACRYLIC COPOLYMER ELASTOMER AND THAT OF FLUORINE-CONTAINING ELASTOMER WHEN BLENDED WITH THE FLUORINE-CONTAINING ELASTOMER NIPPON MEKTRON, LIMITED (JP) 1999-09-28 US disclosed
EP-0765890-B1 Process for producing rubber compound NIPPON MEKTRON KK (JP) 1999-07-21 EP disclosed
US-5859144-A PREPARING AQUEOUS EMULSION OF FLUORINE-CONTAINING ELASTOMER BY EMULSION POLYMERIZATION USING FLUORINE-CONTAINING SURFACTANT, ADDING ACRYLIC MONOMER, REACTING BY RADICAL POLYMERIZATION NIPPON MEKTRON, LIMITED (JP) 1999-01-12 US disclosed
US-5744562-A GOOD HEAT RESISTANCE AND AMINE RESISTANCE WITH FLUORINE-CONTAINING ELASTOMER NIPPON MEKTRON, LIMITED (JP) 1998-04-28 US disclosed
EP-0765890-A2 Process for producing rubber compound NIPPON MEKTRON, LTD. (JP) 1997-04-02 EP disclosed
EP-0761702-A2 Novel acrylic copolymer elastomer, its blend rubber and blend rubber composition NIPPON MEKTRON, LTD. (JP) 1997-03-12 EP disclosed
EP-0755952-A2 Acrylic copolymer elastomer, its blend rubber and blend rubber composition NIPPON MEKTRON, LTD. (JP) 1997-01-29 EP disclosed