Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 4/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008647 | 0.78 | HTR6 (0.50) | HTR6 | |
| SCHEMBL7008649 | 0.78 | HTR6 (0.50) | HTR6 | |
| SCHEMBL3132568 | 0.77 | HTR6 (0.41) | HTR6HTR3A | |
| Hydrochloric Acid SCHEMBL3132503 | 0.76 | HTR6 (0.42) | HTR6HTR3A | |
| SCHEMBL7009126 | 0.76 | HTR6 (0.57) | HTR6 | |
| SCHEMBL7009122 | 0.76 | HTR6 (0.57) | HTR6 | |
| SCHEMBL7007626 | 0.76 | HTR6 (0.52) | HTR6 | |
| SCHEMBL7007623 | 0.76 | HTR6 (0.52) | HTR6 | |
| SCHEMBL7005759 | 0.75 | HTR6 (0.44) | HTR6 | |
| SCHEMBL7005763 | 0.75 | HTR6 (0.44) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874427-A | MIGRAINE | ELI LILLY AND COMPANY (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1998046570-A1 | SUBSTITUTED HETEROAROMATIC 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |