Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 1.00 |
| ▸ | HTR2C | P28335 | 8/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13093266 | 0.89 | QDPR (0.79) | QDPR | |
| SCHEMBL5792003 | 0.89 | QDPR (0.79) | QDPR | |
| SCHEMBL10282755 | 0.85 | QDPR (0.73) | QDPRACMSDMEN1POLBGAA | |
| SCHEMBL108606 | 0.85 | QDPR (0.73) | QDPRACMSDMEN1POLBGAA | |
| SCHEMBL24309416 | 0.83 | QDPR (0.71) | QDPRHTR2CSLC18A3SIGMAR1 | |
| SCHEMBL21527334 | 0.83 | QDPR (0.71) | QDPRHTR2CSLC18A3SIGMAR1ACMSD | |
| SCHEMBL31328458 | 0.83 | QDPR (0.71) | QDPRHTR2CSLC18A3SIGMAR1 | |
| SCHEMBL17395615 | 0.83 | QDPR (0.71) | QDPRHTR2CSLC18A3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL29566349 | 0.82 | QDPR (0.69) | QDPRHTR2CSLC18A3SIGMAR1 | |
| SCHEMBL1291751 | 0.81 | QDPR (0.68) | QDPRACMSDMEN1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874433-A | Blocking utilization of tetrahydrobiopterin to block induction of nitric oxide synthesis | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-02-23 | — | — | US | disclosed |
| US-5502050-A | DIHYDROXYPHENYL-SUBSTITITED PYRIDINES OR QUINONES, HYPERTENSIVE AGENTS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-03-26 | — | — | US | disclosed |