SCHEMBL8385449

SCHEMBL8385449

CCC(C)OC(=O)[N]C(C)C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM1 P11229 1/20 0.30
TBXA2R P21731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL966927 0.79
SCHEMBL968337 0.77 MAPT (0.33) MAPTTSHRCHRM2CHRM4CHRM1
SCHEMBL18698893 0.76 TSHR (0.37) MAPTTSHR
SCHEMBL8383054 0.75 TSHR (0.46) TSHR
SCHEMBL8383425 0.74 MAPT (0.32) MAPT
SCHEMBL223828 0.73
SCHEMBL3982395 0.73
SCHEMBL241530 0.73 FAAH (0.43) MAPTTSHRCHRM2CHRM4CHRM1
SCHEMBL5640470 0.72 CA12 (0.31) MAPT
SCHEMBL5640841 0.72 CA12 (0.31) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5861429-A MITICIDES AND ANTHELMINTICS SANKYO COMPANY, LIMITED (JP) 1999-01-19 US disclosed