Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LSS | P48449 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SQLE | Q14534 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385489 | 1.00 | TSHR (0.56) | TSHRALDH1A1LSSFAAHMAPT | |
| SCHEMBL29284415 | 0.96 | TSHR (0.61) | TSHRALDH1A1LSSFAAHMAPT | |
| SCHEMBL29284458 | 0.92 | TSHR (0.56) | TSHRALDH1A1LSSFAAHMAPT | |
| SCHEMBL29284196 | 0.92 | TSHR (0.56) | TSHRALDH1A1LSSFAAHMAPT | |
| SCHEMBL995861 | 0.92 | TSHR (0.61) | TSHRALDH1A1LSSFAAHMAPT | |
| SCHEMBL29284307 | 0.92 | TSHR (0.56) | TSHRALDH1A1LSSFAAHMAPT | |
| SCHEMBL999077 | 0.90 | TSHR (0.64) | TSHRALDH1A1LSSFAAHMAPT | |
| SCHEMBL29284342 | 0.90 | TSHR (0.56) | TSHRALDH1A1LSSFAAHMAPT | |
| SCHEMBL1136744 | 0.88 | TSHR (0.58) | TSHRALDH1A1LSSMAPTABCC4 | |
| SCHEMBL1136745 | 0.88 | TSHR (0.58) | TSHRALDH1A1LSSMAPTABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570824-B1 | Process for selective reduction of unsaturated organic compounds | GOODYEAR TIRE & RUBBER (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0570824-A2 | Process for selective reduction of unsaturated organic compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-11-24 | — | — | EP | disclosed |
| US-5254761-A | Using mixture of hydrazine and oxidizer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-10-19 | — | — | US | disclosed |