SCHEMBL8385683

SCHEMBL8385683

C=C(C)C(=O)OCCCCCCCCCCCOc1ccc(-c2nc(-c3ccc(C)cc3C)nc(-c3ccc(C)cc3C)n2)c(O)c1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.52
APEX1 P27695 1/20 0.52
HTT P42858 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
TSHR P16473 2/20 0.39
MAOB P27338 8/20 0.36
GAA P10253 1/20 0.36
PLK1 P53350 2/20 0.35
PTPN11 Q06124 1/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
GSTP1 P09211 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30887155 1.00 POLB (0.52) POLBAPEX1HTTTDP1TSHR
SCHEMBL30887231 0.94 HTT (0.43) POLBAPEX1HTTTDP1GAA
SCHEMBL8383168 0.94 HTT (0.43) POLBAPEX1HTTTDP1GAA
SCHEMBL8975412 0.91 HTT (0.61) POLBAPEX1HTTTDP1TSHR
SCHEMBL30887158 0.91 HTT (0.61) POLBAPEX1HTTTDP1TSHR
SCHEMBL30887216 0.91 HTT (0.51) POLBAPEX1HTTTDP1TSHR
SCHEMBL8036053 0.88 POLB (0.37) POLBAPEX1HTTTDP1MAOB
SCHEMBL8383367 0.87 POLB (0.47) POLBAPEX1HTTTDP1TSHR
SCHEMBL30887103 0.87 POLB (0.47) POLBAPEX1HTTTDP1TSHR
SCHEMBL7117619 0.86 PLK1 (0.38) POLBAPEX1HTTTDP1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160200884-A1 FILM COMPRISING VINYLIDENE FLUORIDE RESIN, LAMINATED FILM, AND LAMINATE MITSUBISHI RAYON CO., LTD. (JP) 2016-07-14 US disclosed
EP-3034556-A1 FILM COMPRISING VINYLIDENE FLUORIDE RESIN, LAMINATED FILM, AND LAMINATE Mitsubishi Rayon Co., Ltd. (JP) 2016-06-22 EP disclosed
US-20150116820-A1 FILM MIRROR FOR SOLAR LIGHT REFLECTION, AND REFLECTIVE DEVICE FOR SOLAR POWER GENERATION Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
EP-2796904-A1 FILM MIRROR FOR SOLAR LIGHT REFLECTION, AND REFLECTIVE DEVICE FOR SOLAR POWER GENERATION Konica Minolta, Inc. (JP) 2014-10-29 EP disclosed
US-5869588-A UV ABSORBERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-02-09 US disclosed
US-5672704-A ULTRAVIOLET RADIATION STABILIZERS CIBA-GEIGY CORPORATION 1997-09-30 US disclosed
US-5538840-A SILVER HALIDE EMULSIONS AND POLYMERS ON SUBSTRATES WITH TRIAZINE PHENOLS CIBA-GEIGY CORPORATION (US) 1996-07-23 US disclosed
EP-0706083-A1 Photographic recording material containing an UV-absorber CIBA-GEIGY AG (CH) 1996-04-10 EP disclosed