SCHEMBL8975412

SCHEMBL8975412

C=C(C)C(=O)OCCCCCCCCCCCOc1ccc(-c2nc(-c3ccc(OCCCCCCCCCCCOC(=O)C(=C)C)cc3O)nc(-c3ccc(OCCCCCCCCCCCOC(=O)C(=C)C)cc3O)n2)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.61
POLB P06746 1/20 0.61
APEX1 P27695 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
TSHR P16473 2/20 0.46
GAA P10253 2/20 0.42
MAOB P27338 9/20 0.42
L3MBTL1 Q9Y468 2/20 0.40
PPARD Q03181 1/20 0.39
PTPN11 Q06124 1/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
PDE3B Q13370 1/20 0.38
PDE3A Q14432 1/20 0.38
P2RY12 Q9H244 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30887158 1.00 HTT (0.61) HTTPOLBAPEX1TDP1TSHR
SCHEMBL30887153 0.92 POLB (0.56) HTTPOLBAPEX1TDP1TSHR
SCHEMBL8975634 0.92 POLB (0.56) HTTPOLBAPEX1TDP1TSHR
SCHEMBL8387421 0.92 POLB (0.56) HTTPOLBAPEX1TDP1TSHR
SCHEMBL19466444 0.92 POLB (0.56) HTTPOLBAPEX1TDP1TSHR
SCHEMBL8385683 0.91 POLB (0.52) HTTPOLBAPEX1TDP1TSHR
SCHEMBL30887155 0.91 POLB (0.52) HTTPOLBAPEX1TDP1TSHR
SCHEMBL30887216 0.90 HTT (0.51) HTTPOLBAPEX1TDP1TSHR
SCHEMBL8387123 0.89 POLB (0.53) HTTPOLBAPEX1TDP1TSHR
SCHEMBL30887135 0.89 POLB (0.53) HTTPOLBAPEX1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5538840-A SILVER HALIDE EMULSIONS AND POLYMERS ON SUBSTRATES WITH TRIAZINE PHENOLS CIBA-GEIGY CORPORATION (US) 1996-07-23 US disclosed
EP-0706083-A1 Photographic recording material containing an UV-absorber CIBA-GEIGY AG (CH) 1996-04-10 EP disclosed