Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385756 | 0.96 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTMEN1KMT2AHTT | |
| SCHEMBL7655082 | 0.84 | CES1 (0.49) | MAPTMEN1KMT2ANPC1POLB | |
| Benzoyl Peroxide SCHEMBL10925824 | 0.76 | F2 (0.57) | SMN1; SMN2MAPTMEN1KMT2AHTT | |
| SCHEMBL8387007 | 0.74 | KCNK3 (0.50) | SMN1; SMN2MAPTMEN1KMT2AHTT | |
| SCHEMBL27459060 | 0.72 | CES1 (0.65) | MAPTMEN1KMT2ANPC1CYP2C19 | |
| SCHEMBL27499697 | 0.72 | CES1 (0.70) | MEN1KMT2ANPC1POLBALOX5 | |
| SCHEMBL329271 | 0.71 | F2 (0.65) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL29390229 | 0.71 | F2 (0.65) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| Benzoyl Peroxide SCHEMBL10925823 | 0.71 | F2 (0.65) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL19360854 | 0.71 | ALOX5 (0.67) | SMN1; SMN2MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907666-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997049736-A2 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |