SCHEMBL337801

SCHEMBL337801

CCCCCCCCCCCCCCCCC(Cc1ccccc1)C(C)(C)N

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.55
MMP2 P08253 14/20 0.42
MMP1 P03956 9/20 0.42
MMP3 P08254 9/20 0.42
HTR2A P28223 1/20 0.42
KCNH2 Q12809 1/20 0.41
MMP7 P09237 4/20 0.40
SIGMAR1 Q99720 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2392222 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8387575 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8386222 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8382904 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL25283495 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8386102 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL25287896 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8385145 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8382112 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8381675 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3503927-B1 TOPICAL FORMULATIONS BASED ON IONIC SPECIES FOR SKIN TREATMENT UNIV CALIFORNIA (US) 2025-02-19 EP claimed
EP-4146765-B1 A METHOD AND REAGENTS FOR ENHANCING THE CHEMILUMINESCENT SIGNAL EUROIMMUN MEDIZINISCHE LABORDIAGNOSTIKA AG (DE) 2023-07-05 EP claimed
US-20220089455-A1 METHOD FOR PRODUCING NANOPARTICLE HAVING METAL PARTICLE WHICH CONTAINS IRON OXIDE TO WHICH ONE OR MORE HYDROPHILIC LIGANDS ARE COORDINATION BONDED ASTELLAS PHARMA INC. (JP) 2022-03-24 US claimed
EP-3904294-A1 METHOD FOR PRODUCING NANOPARTICLES INCLUDING METAL PARTICLES CONTAINING IRON OXIDE HAVING AT LEAST ONE HYDROPHILIC LIGAND COORDINATED THERETO Astellas Pharma Inc. (JP) 2021-11-03 EP claimed
CN-113226990-A Method for producing nanoparticles comprising iron oxide-containing metal particles to which one or more hydrophilic ligands are coordinately bound 安斯泰来制药株式会社 2021-08-06 CN claimed
US-20210162050-A1 TOPICAL FORMULATIONS BASED ON IONIC SPECIES FOR SKIN TREATMENT THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-06-03 US claimed
US-10912834-B2 Topical formulations based on ionic species for skin treatment THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-02-09 US claimed
WO-2020138404-A1 METHOD FOR PRODUCING NANOPARTICLES INCLUDING METAL PARTICLES CONTAINING IRON OXIDE HAVING AT LEAST ONE HYDROPHILIC LIGAND COORDINATED THERETO アステラス製薬株式会社 2020-07-02 WO claimed
EP-3240918-B1 MITIGATION OF CORROSION IN GEOTHERMAL SYSTEMS ECOLAB USA INC (US) 2020-04-15 EP claimed
EP-3503927-A1 TOPICAL FORMULATIONS BASED ON IONIC SPECIES FOR SKIN TREATMENT The Regents of the University of California (US) 2019-07-03 EP claimed
US-10252971-B2 Method for producing halogenated acrylic acid derivative AGC Inc. (JP) 2019-04-09 US claimed
WO-2018044920-A1 TOPICAL FORMULATIONS BASED ON IONIC SPECIES FOR SKIN TREATMENT THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-03-08 WO claimed
US-9428521-B2 Process for the production of a carbodiimide KAWAGUCHI CHEMICAL INDUSTRY CO., LTD. (JP) 2016-08-30 US claimed
EP-2583971-B1 METHOD FOR PRODUCING CARBODIIMIDE KAWAGUCHI CHEMICAL INDUSTRY CO LTD (JP) 2015-03-04 EP claimed
EP-2583971-A1 METHOD FOR PRODUCING CARBODIIMIDE Kawaguchi Chemical Industry Co. Ltd. (JP) 2013-04-24 EP claimed
US-20130085274-A1 PROCESS FOR THE PRODUCTION OF A CARBODIIMIDE TEIJIN LIMITED (JP) 2013-04-04 US claimed
EP-0707489-A4 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS INC (US) 1998-07-29 EP claimed
EP-0707489-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF Scotgen Biopharmaceuticals, Inc. (US) 1996-04-24 EP claimed
EP-0385504-B1 Heat-latent curing catalyst and resin compositions containing the same NIPPON PAINT CO LTD (JP) 1995-10-04 EP claimed
WO-1994025053-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS, INC. (US) 1994-11-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130085274-A1 PROCESS FOR THE PRODUCTION OF A CARBODIIMIDE CTH, TST, CBS CSNK1E 731/4885MMP2 2853/4885MMP1 3471/4885
US-20210162050-A1 TOPICAL FORMULATIONS BASED ON IONIC SPECIES FOR SKIN TREATMENT CUTA, KRT18, SLC38A7 CSNK1E 419/4885MMP2 201/4885MMP1 35/4885
US-20220089455-A1 METHOD FOR PRODUCING NANOPARTICLE HAVING METAL PARTICLE WHICH CONTAINS IRON OXIDE TO WHICH ONE OR MORE HYDROPHILIC LIGANDS ARE COORDINATION BONDED FTH1, HAMP, TFRC CSNK1E 4876/4885MMP2 4364/4885MMP1 4406/4885
US-10252971-B2 Method for producing halogenated acrylic acid derivative C3AR1, HRH2, C5AR1 CSNK1E 1219/4885MMP2 2006/4885MMP1 3001/4885
US-10912834-B2 Topical formulations based on ionic species for skin treatment CUTA, KRT18, SLC38A7 CSNK1E 419/4885MMP2 201/4885MMP1 35/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.