SCHEMBL8386178

SCHEMBL8386178

CCCCCCCCCCCCC(C[C@H](N)C(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 4/20 1.00
GRIK2 Q13002 4/20 1.00
SLC1A2 P43004 7/20 0.96
SLC1A1 P43005 6/20 0.96
SLC1A3 P43003 5/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28902633 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL29156799 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL1662288 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL9005456 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL10715048 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL9005462 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL5888741 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL4377664 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL8091382 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL5888744 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621432-B Polyamino acid with capability of inducing cell calcification as well as preparation method and application thereof 中国科学院长春应用化学研究所 2024-02-13 CN claimed
CN-114621432-A Polyamino acid with cell calcification inducing capability and preparation method and application thereof 中国科学院长春应用化学研究所 2022-06-14 CN claimed
CN-114621432-B Polyamino acid with capability of inducing cell calcification as well as preparation method and application thereof 中国科学院长春应用化学研究所 2024-02-13 CN disclosed
CN-114621432-B Polyamino acid with capability of inducing cell calcification as well as preparation method and application thereof 中国科学院长春应用化学研究所 2024-02-13 CN disclosed
CN-114621432-A Polyamino acid with cell calcification inducing capability and preparation method and application thereof 中国科学院长春应用化学研究所 2022-06-14 CN disclosed
CN-114621432-A Polyamino acid with cell calcification inducing capability and preparation method and application thereof 中国科学院长春应用化学研究所 2022-06-14 CN disclosed
EP-0910351-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-28 EP disclosed
EP-0907666-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-14 EP disclosed
WO-1997049736-A2 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
WO-1997049387-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
EP-0572167-B1 Cosmetic composition UNILEVER PLC (GB) 1996-10-09 EP disclosed
EP-0572167-A1 Cosmestic composition UNILEVER PLC (GB) 1993-12-01 EP disclosed