SCHEMBL1662288

SCHEMBL1662288

CCCCCCCCCCCCC(C[C@@H](N)C(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 4/20 1.00
GRIK2 Q13002 4/20 1.00
SLC1A2 P43004 7/20 0.96
SLC1A1 P43005 6/20 0.96
SLC1A3 P43003 5/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28902633 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL29156799 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL9005456 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL8386178 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL10715048 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL9005462 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL5888741 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL4377664 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL8091382 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL5888744 1.00 GRIK1 (1.00) GRIK1GRIK2SLC1A2SLC1A1SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2345526-B1 MOLD FOR NANOIMPRINT TOKYO INST TECH (JP) 2014-02-12 EP disclosed
US-8222359-B2 Poly(propargyl-L-glutamate) and derivatives thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-07-17 US disclosed
US-20110233820-A1 MOLD FOR NANOIMPRINT TOKYO INSTITUTE OF TECHNOLOGY (JP) 2011-09-29 US disclosed
CN-102164733-A Mold for nanoimprint TOKYO INST TECH 2011-08-24 CN disclosed
EP-2345526-A1 MOLD FOR NANOIMPRINT Tokyo Institute of Technology (JP) 2011-07-20 EP disclosed
US-20110097419-A1 Poly(Propargyl-L-Glutamate) and Derivatives Thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2011-04-28 US disclosed
EP-0338702-B1 Nonlinear optical materials NIPPON OIL CO LTD (JP) 1994-06-29 EP disclosed
US-5097016-A Blending a polypeptide or polylactam and a nitro-containing urea, enone, aniline, heterocyclic, stilbene or merocyanine derivative; no secondary harmonic generation; easy phase matching NIPPON OIL CO., LTD. (JP) 1992-03-17 US disclosed
EP-0338702-A1 Nonlinear optical materials NIPPON OIL CO. LTD. (JP) 1989-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110097419-A1 Poly(Propargyl-L-Glutamate) and Derivatives Thereof GLUL, QPCTL, QPCT GRIK1 36/4885GRIK2 47/4885SLC1A2 147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.