SCHEMBL8386296

SCHEMBL8386296

NC(=O)/C=C/CCCC/C=C/C(N)=O

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.47
ALDH1A1 P00352 1/20 0.47
FAAH O00519 3/20 0.43
SOAT1 P35610 2/20 0.43
MEN1 O00255 1/20 0.43
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43
KMT2A Q03164 1/20 0.43
CNR1 P21554 1/20 0.40
KDM4E B2RXH2 2/20 0.39
PPARG P37231 2/20 0.36
PPARA Q07869 2/20 0.36
PTPN1 P18031 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8386298 1.00 MAPT (0.47) MAPTALDH1A1FAAHSOAT1MEN1
SCHEMBL3425032 0.97 ALDH1A1 (0.50) MAPTALDH1A1FAAHSOAT1MEN1
SCHEMBL8742216 0.97 ALDH1A1 (0.50) MAPTALDH1A1FAAHSOAT1MEN1
SCHEMBL2089612 0.97 ALDH1A1 (0.50) MAPTALDH1A1FAAHSOAT1MEN1
SCHEMBL11335978 0.97 ALDH1A1 (0.50) MAPTALDH1A1FAAHSOAT1MEN1
SCHEMBL3425033 0.97 ALDH1A1 (0.50) MAPTALDH1A1FAAHSOAT1MEN1
SCHEMBL435734 0.97 ALDH1A1 (0.50) MAPTALDH1A1FAAHSOAT1MEN1
SCHEMBL4245664 0.97 ALDH1A1 (0.50) MAPTALDH1A1FAAHSOAT1MEN1
SCHEMBL2088482 0.97 ALDH1A1 (0.50) MAPTALDH1A1FAAHSOAT1MEN1
SCHEMBL4806523 0.97 ALDH1A1 (0.50) MAPTALDH1A1FAAHSOAT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0802928-B1 USE OF POLYGLYCEROL ALIPHATIC ETHER EMULSIFIERS IN MAKING HIGH INTERNAL PHASE EMULSIONS THAT CAN BE POLYMERIZED TO PROVIDE ABSORBENT FOAMS PROCTER & GAMBLE (US) 1999-06-16 EP claimed
EP-0802803-B1 BIODEGRADABLE AND/OR COMPOSTABLE POLYMERS MADE FROM CONJUGATED DIENES SUCH AS ISOPRENE AND 2,3-DIMETHYL-1,3-BUTADIENE PROCTER & GAMBLE (US) 1999-05-19 EP claimed
EP-0802802-B1 CROSS-LINKED POLYMERS MADE FROM 1,3,7-OCTATRIENE AND LIKE CONJUGATED POLYENES PROCTER & GAMBLE (US) 1999-04-14 EP claimed