SCHEMBL8386705

SCHEMBL8386705

CCOc1ccc(PO)cc1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.64
LTA4H P09960 2/20 0.57
TDP1 Q9NUW8 2/20 0.52
TSHR P16473 1/20 0.52
PARP10 Q53GL7 1/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
ADRA2A P08913 2/20 0.47
MAPT P10636 1/20 0.47
NPC1 O15118 1/20 0.46
PLK1 P53350 1/20 0.46
POLB P06746 1/20 0.46
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9502203 0.81 NQO1 (0.70) NQO1LTA4HTDP1TSHRPARP10
1,4-Diethoxybenzene SCHEMBL124015 0.80 NQO1 (1.00) NQO1LTA4HTDP1TSHRPARP10
1,4-Diethoxybenzene SCHEMBL28186701 0.80 NQO1 (1.00) NQO1LTA4HTDP1TSHRPARP10
Bromide SCHEMBL28918405 0.79 NQO1 (0.67) NQO1LTA4HTDP1TSHRPARP10
Hydrochloric Acid SCHEMBL2154481 0.79 NQO1 (0.67) NQO1LTA4HTDP1TSHRPARP10
1-Hydroxy-4-Ethoxybenzene SCHEMBL12476725 0.78 LTA4H (0.86) NQO1LTA4HTDP1TSHRPARP10
1-Hydroxy-4-Ethoxybenzene SCHEMBL28520 0.78 LTA4H (0.86) NQO1LTA4HTDP1TSHRPARP10
SCHEMBL27586330 0.77 NQO1 (0.64) NQO1LTA4HTDP1TSHRPARP10
1,4-Diethoxybenzene SCHEMBL11794798 0.77 NQO1 (0.93) NQO1LTA4HTDP1TSHRPARP10
1-Hydroxy-4-Ethoxybenzene SCHEMBL8054038 0.76 LTA4H (0.83) NQO1LTA4HTDP1TSHRPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487343-B1 Process for preparing a lithographic plate FUJI PHOTO FILM CO LTD (JP) 1999-04-28 EP disclosed
EP-0487343-A1 Process for preparing a lithographic plate Fuji Photo Film Co., Ltd. (JP) 1992-05-27 EP disclosed