SCHEMBL8387282

SCHEMBL8387282

CCCCCCCCCCNC(=O)CCCCCCCCCCSc1ccc(O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.60
CASP2 P42575 1/20 0.50
HDAC3 O15379 2/20 0.49
HDAC4 P56524 2/20 0.49
HDAC1 Q13547 2/20 0.49
HDAC7 Q8WUI4 2/20 0.49
HDAC2 Q92769 2/20 0.49
HDAC10 Q969S8 2/20 0.49
HDAC11 Q96DB2 2/20 0.49
HDAC8 Q9BY41 2/20 0.49
HDAC6 Q9UBN7 2/20 0.49
HDAC9 Q9UKV0 2/20 0.49
HDAC5 Q9UQL6 2/20 0.49
FAAH O00519 3/20 0.49
CNR1 P21554 2/20 0.48
CNR2 P34972 2/20 0.48
HSD17B10 Q99714 1/20 0.48
THRA P10827 1/20 0.48
THRB P10828 1/20 0.48
TRPV1 Q8NER1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8626774 1.00 HPGD (0.60) HPGDCASP2HDAC3HDAC4HDAC1
SCHEMBL8623426 1.00 HPGD (0.60) HPGDCASP2HDAC3HDAC4HDAC1
SCHEMBL8624394 0.92 HPGD (0.71) HPGDCASP2TRPV1KDM4EMEN1
SCHEMBL8391748 0.92 HPGD (0.59) HPGDFAAHCNR1CNR2HSD17B10
SCHEMBL8389328 0.92 HPGD (0.71) HPGDCASP2TRPV1KDM4EMEN1
SCHEMBL8391390 0.91 THRA (0.52) HPGDHDAC3HDAC4HDAC1HDAC7
SCHEMBL8624190 0.88 HDAC1 (0.52) HPGDHDAC3HDAC4HDAC1HDAC7
SCHEMBL8389664 0.88 HPGD (0.50) HPGDCNR2THRATHRBNAAA
SCHEMBL8390581 0.88 CNR2 (0.57) HPGDCNR2THRATHRBNAAA
SCHEMBL8623969 0.88 CNR2 (0.57) HPGDCNR2THRATHRBNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6004899-A SURFACE TREATED WITH SILANE, TITANATE, AND/OR ALUMINUM COUPLING AGENT; PIGMENT; ERASIBILITY MITSUBISHI PAPER MILLS LIMITED (JP) 1999-12-21 US disclosed
EP-0648612-B1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1998-06-10 EP disclosed
US-5498772-A SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER MITSUBISHI PAPER MILLS LIMITED (JP) 1996-03-12 US disclosed
EP-0648612-A1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1995-04-19 EP disclosed