Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8504672 | 0.88 | MAPT (0.39) | MAPT | |
| SCHEMBL27338205 | 0.88 | EGFR (0.31) | LMNAHSD17B10 | |
| SCHEMBL7059830 | 0.87 | TSHR (0.35) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL20260601 | 0.83 | MAPT (0.38) | MAPTLMNAHSD17B10TSHRCYP3A4 | |
| SCHEMBL15780155 | 0.83 | MAPT (0.40) | MAPTHSD17B10TSHRTDP1 | |
| SCHEMBL27338212 | 0.79 | CYP3A4 (0.51) | LMNAHSD17B10TSHRCYP3A4TDP1 | |
| SCHEMBL27338207 | 0.77 | EGFR (0.32) | MAPT | |
| SCHEMBL30877065 | 0.77 | TSHR (0.33) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL27338230 | 0.77 | LMNA (0.34) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL7125831 | 0.76 | TSHR (0.37) | LMNATSHRCYP3A4NFKB1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908450-A2 | Novel polyfunctional peroxides, vinyl monomer polymerization initiators comprising the same and process for polymerizing vinyl monomers employing the same | NOF CORPORATION (JP) | 1999-04-14 | — | — | EP | disclosed |