SCHEMBL8387392

SCHEMBL8387392

CCCCCCC(=O)Nc1ccc(O)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB11 A5LHX3 2/20 0.83
PSMA7 O14818 2/20 0.83
PSMB1 P20618 2/20 0.83
PSMA1 P25786 2/20 0.83
PSMA2 P25787 2/20 0.83
PSMA3 P25788 2/20 0.83
PSMA4 P25789 2/20 0.83
PSMB8 P28062 2/20 0.83
PSMB9 P28065 2/20 0.83
PSMA5 P28066 2/20 0.83
PSMB4 P28070 2/20 0.83
PSMB6 P28072 2/20 0.83
PSMB5 P28074 2/20 0.83
PSMB10 P40306 2/20 0.83
PSMB3 P49720 2/20 0.83
PSMB2 P49721 2/20 0.83
PSMA6 P60900 2/20 0.83
PSMA8 Q8TAA3 2/20 0.83
PSMB7 Q99436 2/20 0.83
CNR1 P21554 5/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7271399 1.00 PSMB11 (0.83) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL7262780 1.00 PSMB11 (0.83) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL39445 1.00 PSMB11 (0.83) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL38999 1.00 PSMB11 (0.83) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL2720795 1.00 PSMB11 (0.83) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL1133530 1.00 PSMB11 (0.83) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL39282 1.00 PSMB11 (0.83) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL13510734 1.00 PSMB11 (0.83) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL7264242 1.00 PSMB11 (0.83) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL7270436 1.00 PSMB11 (0.83) PSMB11PSMA7PSMB1PSMA1PSMA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210332001-A1 SYNTHESIS AND ANTI-TUMOR ACTIVITIES OF ACYL-PARA-AMINOPHENOL DERIVATIVES MONTEFIORE MEDICAL CENTER 2021-10-28 US claimed
EP-0091519-B1 TOPICAL ACYLAMINOPHENOLS Johnson & Johnson Products Inc. (US) 1987-06-24 EP claimed
EP-0091519-A1 Topical acylaminophenols Johnson & Johnson Products Inc. (US) 1983-10-19 EP claimed
US-4329366-A ANTIINFLAMMATORY AGENTS JOHNSON & JOHNSON PRODUCTS, INC. (US) 1982-05-11 US claimed
US-20210332001-A1 SYNTHESIS AND ANTI-TUMOR ACTIVITIES OF ACYL-PARA-AMINOPHENOL DERIVATIVES MONTEFIORE MEDICAL CENTER 2021-10-28 US disclosed
US-20210332001-A1 SYNTHESIS AND ANTI-TUMOR ACTIVITIES OF ACYL-PARA-AMINOPHENOL DERIVATIVES MONTEFIORE MEDICAL CENTER 2021-10-28 US disclosed
US-8987226-B2 Modified single-stranded polynucleotides DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-03-24 US disclosed
US-6004899-A SURFACE TREATED WITH SILANE, TITANATE, AND/OR ALUMINUM COUPLING AGENT; PIGMENT; ERASIBILITY MITSUBISHI PAPER MILLS LIMITED (JP) 1999-12-21 US disclosed
EP-0574879-B1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1997-05-02 EP disclosed
US-5395815-A Phenolic compound electron acceptor; images; contrast; stability MITSUBISHI PAPER MILLS LIMITED (JP) 1995-03-07 US disclosed
EP-0574879-A1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1993-12-22 EP disclosed
EP-0091519-B1 TOPICAL ACYLAMINOPHENOLS Johnson & Johnson Products Inc. (US) 1987-06-24 EP disclosed
EP-0091519-A1 Topical acylaminophenols Johnson & Johnson Products Inc. (US) 1983-10-19 EP disclosed
US-4329366-A ANTIINFLAMMATORY AGENTS JOHNSON & JOHNSON PRODUCTS, INC. (US) 1982-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210332001-A1 SYNTHESIS AND ANTI-TUMOR ACTIVITIES OF ACYL-PARA-AMINOPHENOL DERIVATIVES AADAC, FABP7, NPEPPS PSMB11 1050/4885PSMA7 678/4885PSMB1 1084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.