Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595095 | 0.90 | GPR139 (0.55) | GPR139ALDH1A1KMT2AMAPTHTT | |
| SCHEMBL14417102 | 0.87 | GPR139 (0.52) | GPR139ALDH1A1KMT2AMAPTHTT | |
| SCHEMBL1055212 | 0.87 | GPR139 (0.52) | GPR139ALDH1A1KMT2AMAPTHTT | |
| SCHEMBL16088020 | 0.87 | GPR139 (0.47) | GPR139ALDH1A1KMT2AMAPTHTT | |
| SCHEMBL10297351 | 0.84 | KMT2A (0.47) | GPR139ALDH1A1KMT2AMAPTHTT | |
| SCHEMBL19034783 | 0.84 | GPR139 (0.54) | GPR139ALDH1A1KMT2AMAPTHTT | |
| SCHEMBL16089542 | 0.84 | GPR139 (0.50) | GPR139ALDH1A1KMT2AMAPTHTT | |
| SCHEMBL19632907 | 0.83 | GPR139 (0.47) | GPR139ALDH1A1KMT2AMAPTHTT | |
| SCHEMBL10720966 | 0.83 | GPR139 (0.49) | GPR139ALDH1A1KMT2AMAPTHTT | |
| SCHEMBL10309087 | 0.83 | KMT2A (0.51) | GPR139ALDH1A1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858327-A | CONJUGATION TO TARGETTING AND LABELLING BIOMOLECULES LIKE PROTEINS, PEPTIDES AND ANTIBODIES; CONTRAST AGENTS FOR TOMAGRAPHY DIAGNOSIS | RESOLUTIONS PHARMACEUTICALS, INC. (CA) | 1999-01-12 | — | — | US | claimed |
| US-5858327-A | CONJUGATION TO TARGETTING AND LABELLING BIOMOLECULES LIKE PROTEINS, PEPTIDES AND ANTIBODIES; CONTRAST AGENTS FOR TOMAGRAPHY DIAGNOSIS | RESOLUTIONS PHARMACEUTICALS, INC. (CA) | 1999-01-12 | — | — | US | disclosed |
| US-5574140-A | LABELS FOR TARGETS MOLECULES FOR DIAGNOSIS | RESOLUTION PHARMACEUTICAL INC. (CA) | 1996-11-12 | — | — | US | disclosed |
| EP-0716647-A1 | HYDRAZINO-TYPE N 2?S 2? CHELATORS | RESOLUTION PHARMACEUTICALS INC. (CA) | 1996-06-19 | — | — | EP | disclosed |
| WO-1995006633-A1 | HYDRAZINO-TYPE N2S2 CHELATORS | RESOLUTION PHARMACEUTICALS INC. (CA) | 1995-03-09 | — | — | WO | disclosed |