Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.73 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.73 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.73 |
| ▸ | GRIK1 | P39086 | 9/20 | 0.60 |
| ▸ | GRIK2 | Q13002 | 7/20 | 0.60 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.60 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.50 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8384161 | 1.00 | SLC1A1 (0.73) | SLC1A1SLC1A3SLC1A2GRIK1GRIK2 | |
| SCHEMBL13725911 | 0.85 | SLC1A1 (0.75) | SLC1A1SLC1A3SLC1A2GRIK1SLC7A5 | |
| SCHEMBL13725557 | 0.85 | SLC1A1 (0.75) | SLC1A1SLC1A3SLC1A2GRIK1SLC7A5 | |
| SCHEMBL1819024 | 0.85 | SLC1A1 (0.75) | SLC1A1SLC1A3SLC1A2GRIK1SLC7A5 | |
| SCHEMBL133913 | 0.84 | SLC1A1 (1.00) | SLC1A1SLC1A3SLC1A2GRIK1SLC7A5 | |
| SCHEMBL8377822 | 0.84 | SLC1A1 (1.00) | SLC1A1SLC1A3SLC1A2GRIK1SLC7A5 | |
| SCHEMBL2265548 | 0.84 | SLC1A1 (1.00) | SLC1A1SLC1A3SLC1A2GRIK1SLC7A5 | |
| SCHEMBL130817 | 0.84 | SLC1A1 (1.00) | SLC1A1SLC1A3SLC1A2GRIK1SLC7A5 | |
| Fenclonine SCHEMBL26383 | 0.84 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP | |
| Fenclonine SCHEMBL26382 | 0.84 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910351-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0907666-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997049736-A2 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| WO-1997049387-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |