SCHEMBL8388

SCHEMBL8388

CC([O])CN(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1920833 0.74 HTR2A (0.33)
SCHEMBL30567674 0.71
SCHEMBL27669385 0.71 ALDH1A1 (0.33)
SCHEMBL8060724 0.71
SCHEMBL135840 0.71
SCHEMBL11832323 0.69
SCHEMBL1005729 0.69 HTR2A (0.35)
SCHEMBL91203 0.69
SCHEMBL14804679 0.69
SCHEMBL4716128 0.69 MEN1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106663614-A Selective deposition using selective reduction and protection of alcohols 应用材料公司 2017-05-10 CN claimed
US-20100240654-A1 HYDRAZIDE DERIVATIVES CLARK RICHARD 2010-09-23 US claimed
US-20100234400-A1 COMPOUNDS THAT MAINTAIN PLURIPOTENCY OF EMBRYONIC STEM CELLS IRM LLC (BM) 2010-09-16 US claimed
US-20080132507-A1 Hydrazide Derivatives EISAI R&D MANAGEMENT CO., LTD. (JP) 2008-06-05 US claimed
US-7371750-B2 Diseases with abnormal activation of the Abl, BCR-Abl, Bmx, CSK, TrkB, FGFR3, Fes, Lck, B-RAF, C-RAF, MKK6, alpha and beta SAPK2 kinases; antiproliferative; pyrrolo[2,3-d]pyrimidine-7-carboxylic acid [3-phenylcarbamoyl-phenyl]-amides and pyrrolo[3,2-c]pyridine analogs IRM LLC (BM) 2008-05-13 US claimed
EP-1899344-A1 COMPOUNDS THAT MAINTAIN PLURIPOTENCY OF EMBRYONIC STEM CELLS IRM, LLC (BM) 2008-03-19 EP claimed
EP-1810965-A1 HYDRAZIDE DERIVATIVES Eisai R&D Management Co., Ltd. (JP) 2007-07-25 EP claimed
WO-2006135824-A1 COMPOUNDS THAT MAINTAIN PLURIPOTENCY OF EMBRYONIC STEM CELLS IRM LLC (BM) 2006-12-21 WO claimed
US-20050222177-A1 Compounds and compositions as protein kinase inhibitors IRM LLC (BM) 2005-10-06 US claimed
US-5438050-A Indolocarbazole derivatives, processes for their preparation and compositions containing them GODECKE AKTIENGESELLSCHAFT (DE) 1995-08-01 US claimed
US-5380746-A Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them GOEDECKE AKTIENGESELLSCHAFT (DE) 1995-01-10 US claimed
EP-0370236-B1 INDOLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS GÖDECKE AKTIENGESELLSCHAFT (DE) 1991-12-27 EP claimed
EP-0370236-A1 Indolocarbazole derivatives, processes for their preparation and their use as medicaments GÖDECKE AKTIENGESELLSCHAFT (DE) 1990-05-30 EP claimed
US-4917989-A MULTILAYER; TRANSPARENT SUBSTRATE, DYE AND REFLECTOR BASF AKTIENGESELLSCHAFT (DE) 1990-04-17 US claimed
CN-114423742-B Benzotriazole-based compound, light absorber and resin composition 三井化学株式会社 2024-05-28 CN disclosed
CN-117466830-A Benzotriazole-based compound, light absorber and resin composition 三井化学株式会社 2024-01-30 CN disclosed
WO-2024005030-A1 DIPHENYLETHENE-BASED COMPOUND, LIGHT ABSORBER, RESIN COMPOSITION, AND USE THEREOF 山本化成株式会社 2024-01-04 WO disclosed
EP-0397060-A2 Maleinimide derivatives and their use as medicines GÖDECKE AKTIENGESELLSCHAFT (DE) 1990-11-14 EP disclosed
US-4917989-A MULTILAYER; TRANSPARENT SUBSTRATE, DYE AND REFLECTOR BASF AKTIENGESELLSCHAFT (DE) 1990-04-17 US disclosed
EP-0291848-A2 Optical-recording medium comprising a reflective layer containing a silicon-phthalocyanin compound BASF Aktiengesellschaft (DE) 1988-11-23 EP disclosed