Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.48 |
| ▸ | YAP1 | P46937 | 1/20 | 0.48 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.48 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 3/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388519 | 0.90 | EPHX1 (0.54) | HPGDNAAAALDH1A1MTNR1AMTNR1B | |
| SCHEMBL8624633 | 0.90 | HPGD (0.50) | HPGDTEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL8388750 | 0.90 | EPHX1 (0.54) | HPGDNAAAALDH1A1MTNR1AMTNR1B | |
| SCHEMBL8587990 | 0.90 | HPGD (0.50) | HPGDTEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL8624394 | 0.89 | HPGD (0.71) | HPGDNAAATRPV1CASP2KDM4E | |
| SCHEMBL8391748 | 0.89 | HPGD (0.59) | HPGDTEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL8389328 | 0.89 | HPGD (0.71) | HPGDNAAATRPV1CASP2KDM4E | |
| SCHEMBL9808073 | 0.87 | TEAD1 (0.60) | HPGDTEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL8387282 | 0.86 | HPGD (0.60) | HPGDNAAATRPV1CASP2KDM4E | |
| SCHEMBL8623426 | 0.86 | HPGD (0.60) | HPGDNAAATRPV1CASP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004899-A | SURFACE TREATED WITH SILANE, TITANATE, AND/OR ALUMINUM COUPLING AGENT; PIGMENT; ERASIBILITY | MITSUBISHI PAPER MILLS LIMITED (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0648612-B1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD (JP) | 1998-06-10 | — | — | EP | disclosed |
| EP-0648612-A1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |