Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 1/20 | 0.42 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8587990 | 1.00 | HPGD (0.50) | HPGDNAAASMN1; SMN2ALOX12MTNR1A | |
| SCHEMBL8389664 | 0.94 | HPGD (0.50) | HPGDNAAASMN1; SMN2ALOX12MAOB | |
| SCHEMBL8389466 | 0.94 | HPGD (0.50) | HPGDNAAASMN1; SMN2ALOX12MAOB | |
| SCHEMBL8388519 | 0.91 | EPHX1 (0.54) | HPGDNAAAMTNR1AMTNR1BMAOB | |
| SCHEMBL8388750 | 0.91 | EPHX1 (0.54) | HPGDNAAAMTNR1AMTNR1BMAOB | |
| SCHEMBL8388484 | 0.90 | HPGD (0.56) | HPGDNAAAMTNR1AMTNR1BMAOB | |
| SCHEMBL9808094 | 0.86 | TEAD1 (0.53) | HPGDSMN1; SMN2MTNR1AMTNR1BTEAD1 | |
| SCHEMBL8390581 | 0.86 | CNR2 (0.57) | HPGDNAAAEPHX2PLK1CNR2 | |
| SCHEMBL8391587 | 0.86 | EPHX1 (0.54) | HPGDNAAAEPHX2PLK1CNR2 | |
| SCHEMBL8623969 | 0.86 | CNR2 (0.57) | HPGDNAAAEPHX2PLK1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648612-B1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5498772-A | SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER | MITSUBISHI PAPER MILLS LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0648612-A1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |