Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 8/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.42 |
| ▸ | PTGFR | P43088 | 3/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.42 |
| ▸ | PTGIR | P43119 | 2/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10865615 | 0.87 | NPSR1 (0.47) | NPSR1EGFRPTGER3PTGER2PTGDR | |
| SCHEMBL3930354 | 0.84 | MIF (0.55) | EGFRPTGER3PTGER2PTGDRTBXA2R | |
| SCHEMBL1174440 | 0.82 | NPSR1 (0.49) | NPSR1EGFRPTGER3PTGER2PTGDR | |
| SCHEMBL1174443 | 0.82 | NPSR1 (0.49) | NPSR1EGFRPTGER3PTGER2PTGDR | |
| SCHEMBL11791639 | 0.81 | ATG4B (0.43) | NPSR1SMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL11791653 | 0.81 | ATG4B (0.43) | NPSR1SMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL11791976 | 0.80 | ATG4B (0.45) | — | |
| SCHEMBL11791982 | 0.80 | ATG4B (0.45) | — | |
| SCHEMBL10351248 | 0.79 | PTGER3 (0.58) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL10906979 | 0.78 | NPSR1 (0.42) | NPSR1EGFRPTGER3PTGER2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1089755-C | Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents | PHARMACIA & UPJOHN SPA (IT) | 2002-08-28 | — | — | CN | disclosed |
| CN-1222144-A | Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents | PHARMACIA & UPJOHN SPA (IT) | 1999-07-07 | — | — | CN | disclosed |
| EP-0912509-A1 | DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AND ANTIVIRAL AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997043258-A1 | DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AND ANTIVIRAL AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-11-20 | — | — | WO | disclosed |