⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163698 | 0.77 | — | — | |
| SCHEMBL9131744 | 0.73 | — | — | |
| SCHEMBL1655666 | 0.73 | — | — | |
| SCHEMBL8960421 | 0.73 | LMNA (0.30) | — | |
| SCHEMBL7162066 | 0.71 | — | — | |
| SCHEMBL972049 | 0.71 | — | — | |
| SCHEMBL10618760 | 0.69 | — | — | |
| SCHEMBL7161342 | 0.67 | — | — | |
| SCHEMBL13355 | 0.65 | — | — | |
| SCHEMBL1454347 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1084190-C | Dermatologic preparation composition containing prostacyclin as active ingredient | TEIJIN LTD (JP) | 2002-05-08 | — | — | CN | disclosed |
| US-5965611-A | TREATING CHRONIC PERIPHERAL ARTERIAL OCCLUSION BY ADMINISTERING EMULSION COMPRISING ISOCARBACYCLIN, VEGETABLE OIL, PHOSPHOLIPID, AND WATER | TEIGIN LIMITED (JP) | 1999-10-12 | — | — | US | disclosed |
| EP-0634171-B1 | PHARMACEUTICAL COMPOSITION FOR TREATING CEREBRAL THROMBOSIS | TEIJIN LTD (JP) | 1999-05-06 | — | — | EP | disclosed |
| EP-0761225-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING PERIPHERAL CIRCULATION DISORDER | TEIJIN LIMITED (JP) | 1997-03-12 | — | — | EP | disclosed |
| US-5610182-A | ADMINISTERING AN ISOCARBACYCLIN OF SPECIFIC STRUCTURE IN THE FORM OF A FAT EMULSION | TEIJIN, LIMITED (JP) | 1997-03-11 | — | — | US | disclosed |
| CN-1102038-A | External skin therapeutic agent composition containing prostacyclin as active ingredient | TEIJIN LTD (JP) | 1995-04-26 | — | — | CN | disclosed |
| EP-0634171-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING CEREBRAL THROMBOSIS | TEIJIN LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |