Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 12/20 | 0.77 |
| ▸ | MAPK12 | P53778 | 12/20 | 0.77 |
| ▸ | MAPK11 | Q15759 | 12/20 | 0.77 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.77 |
| ▸ | GCGR | P47871 | 10/20 | 0.77 |
| ▸ | RAF1 | P04049 | 4/20 | 0.77 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.75 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.64 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.60 |
| ▸ | TEK | Q02763 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469323 | 0.99 | MAPK13 (0.79) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL6164173 | 0.99 | MAPK13 (0.79) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL6464698 | 0.92 | NOX1 (0.74) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL15075611 | 0.92 | MAPK13 (0.89) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL2649730 | 0.88 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL6471005 | 0.88 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL6469341 | 0.87 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL2648503 | 0.86 | MAPK11 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL6467858 | 0.85 | MAPK14 (0.74) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL15400824 | 0.85 | NOX1 (0.85) | MAPK13MAPK12MAPK11MAPK14GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955480-A | GLUCAGON RECEPTOR ANTAGONISTS, CYTOKINE INHIBITORS | MERCK & CO., INC. (US) | 1999-09-21 | — | — | US | disclosed |