SCHEMBL8389178

SCHEMBL8389178

CC(C=O)C(CC(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.37
SLC22A6 Q4U2R8 1/20 0.35
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
CACNA2D1 P54289 2/20 0.33
CACNB3 P54284 1/20 0.33
CACNA1C Q13936 1/20 0.33
CYP1A2 P05177 1/20 0.33
PGR P06401 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
CACNA2D2 Q9NY47 1/20 0.33
CASP1 P29466 1/20 0.33
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
MMP9 P14780 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11734818 0.80 TDP1 (0.54) TDP1SMN1; SMN2SLC22A6SLC1A3SLC1A2
SCHEMBL17883364 0.79 TDP1 (0.37) TDP1SLC1A3SLC1A2SLC1A1ADRA1A
SCHEMBL3332161 0.79 TDP1 (0.37) TDP1SLC1A3SLC1A2SLC1A1ADRA1A
SCHEMBL5554366 0.78 TDP1 (0.52) TDP1SMN1; SMN2SLC22A6SLC1A3SLC1A2
SCHEMBL4257257 0.78 MEN1 (0.38) TDP1SMN1; SMN2
SCHEMBL554957 0.75 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6SLC1A3SLC1A2
SCHEMBL5514949 0.75 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6SLC1A3SLC1A2
Formic Acid SCHEMBL20836208 0.75 TDP1 (0.78) TDP1SMN1; SMN2SLC22A6FOLH1
SCHEMBL14803500 0.75 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6SLC1A3SLC1A2
SCHEMBL9911939 0.74 TDP1 (0.59) TDP1SMN1; SMN2SLC22A6CACNA2D1CACNB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399755-B1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates FUJI PHOTO FILM CO LTD (JP) 1994-03-30 EP claimed
US-5112743-A Aromatic-aldehyde diazo resins FUJI PHOTO FILM CO., LTD. (JP) 1992-05-12 US claimed
EP-0399755-A1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates Fuji Photo Film Co., Ltd. (JP) 1990-11-28 EP claimed
EP-0487343-B1 Process for preparing a lithographic plate FUJI PHOTO FILM CO LTD (JP) 1999-04-28 EP disclosed
EP-0399755-B1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates FUJI PHOTO FILM CO LTD (JP) 1994-03-30 EP disclosed
EP-0487343-A1 Process for preparing a lithographic plate Fuji Photo Film Co., Ltd. (JP) 1992-05-27 EP disclosed
US-5112743-A Aromatic-aldehyde diazo resins FUJI PHOTO FILM CO., LTD. (JP) 1992-05-12 US disclosed
EP-0399755-A1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates Fuji Photo Film Co., Ltd. (JP) 1990-11-28 EP disclosed