Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | RARG | P13631 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.58 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.58 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.58 |
| ▸ | CPA1 | P15085 | 7/20 | 0.56 |
| ▸ | CPA3 | P15088 | 3/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.56 |
| ▸ | CPB1 | P15086 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL838961 | 1.00 | CYP1A2 (0.63) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6154521 | 1.00 | CYP1A2 (0.63) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL6572922 | 0.98 | CYP1A2 (0.61) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL6572923 | 0.98 | CYP1A2 (0.61) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Benzoquinone SCHEMBL28513425 | 0.94 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8861587 | 0.91 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7319468 | 0.91 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6572920 | 0.87 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6573900 | 0.87 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9808996 | 0.87 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583903-B | Method for rapidly preparing racecadotril | 湖北广辰药业有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-115583903-A | Method for rapidly preparing racecadotril | 湖北广辰药业有限公司 | 2023-01-10 | — | — | CN | claimed |
| CN-109942468-B | Process method for preparing cadotril from 3-phenyl-1-propyne | 大连万福制药有限公司 | 2020-09-29 | — | — | CN | claimed |
| EP-0820439-B1 | METHOD FOR THE ASYMMETRICAL SYNTHESIS OF S-ACYLATED DERIVATIVES OF 2-MERCAPTOMETHYL 3-PHENYL PROPANOIC ACID, AND USE THEREOF FOR SYNTHESISING N-(MERCAPTOACYL) AMINO ACID DERIVATIVES | BIOPROJET SOC CIV (FR) | 2000-05-03 | — | — | EP | claimed |
| US-6013829-A | REDUCING A MALONIC DIESTER, HYDRIDING TO OBTAIN A DIOL, ACETYLATING TO OBTAIN A MONOESTER, OXIDATION, SAPONIFICATION AND THIOACYLATING; ENZYME INHIBITORS; PROTEASES; OPTICS; ANTISECRETORY AND HYPOTENSIVE AGENTS | SOCIETE CIVILE BIOPROJET (FR) | 2000-01-11 | — | — | US | claimed |
| EP-0318377-B1 | ENANTIOMERIC DERIVATIVES OF AMINO ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL APPLICATIONS | SOCIETE CIVILE BIOPROJET (FR) | 1993-08-25 | — | — | EP | claimed |
| US-5136076-A | Splitting of racemic 3-acetylthio-2-benzyl propionic acid by reaction with ephedrin, separation of salts, freeing of the acid and coupling with the corresponding amino acid ester | SOCIETE CIVILE BIOPROJET (FR) | 1992-08-04 | — | — | US | claimed |
| JP-8059606-A | — | — | None | — | — | JP | disclosed |
| JP-11228532-A | — | — | None | — | — | JP | disclosed |
| CN-115583903-B | Method for rapidly preparing racecadotril | 湖北广辰药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-115583903-B | Method for rapidly preparing racecadotril | 湖北广辰药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-115583903-A | Method for rapidly preparing racecadotril | 湖北广辰药业有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-115583903-A | Method for rapidly preparing racecadotril | 湖北广辰药业有限公司 | 2023-01-10 | — | — | CN | disclosed |
| EP-0110484-A1 | Derivatives of aminopyridinecarboxylic acids, methods for their preparation and pharmaceutical compositions containing them | Simes S.p.A. (IT) | 1984-06-13 | — | — | EP | disclosed |
| EP-0038046-B1 | PHARMACEUTICAL AMIDES, AND PREPARATION, FORMULATIONS AND USE THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-02-29 | — | — | EP | disclosed |
| EP-0038046-A2 | Pharmaceutical amides, and preparation, formulations and use thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-10-21 | — | — | EP | disclosed |
| US-4263293-A | ANTIARTHRITIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1981-04-21 | — | — | US | disclosed |
| US-4154840-A | Antihypertensive pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4105776-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-08-08 | — | — | US | disclosed |
| US-4046889-A | HYPOTENSIVE AGENTS, ENZYME INHIBITORS, ANGIOTENSIN CONVERSION | E. R. SQUIBB & SONS, INC. (US) | 1977-09-06 | — | — | US | disclosed |