SCHEMBL839017

SCHEMBL839017

C[SiH2]OCC(OC(C)=O)OC(C)=O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.41
TSHR P16473 2/20 0.39
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM1 P11229 1/20 0.34
TBXA2R P21731 1/20 0.34
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
HRH1 P35367 1/20 0.33
KMT2A Q03164 1/20 0.33
GALR3 O60755 1/20 0.33
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23529408 0.78 TSHR (0.36) TDP1TSHRCHRM2CHRM4CHRM1
SCHEMBL28742922 0.75 TSHR (0.46) TDP1TSHRCHRM2CHRM4CHRM1
SCHEMBL15841437 0.75 TSHR (0.33) TDP1TSHRCHRM2CHRM4CHRM1
SCHEMBL29562505 0.74 TSHR (0.32) TDP1TSHR
SCHEMBL1079198 0.73 TDP1 (0.56) TDP1TSHRCHRM2CHRM4CHRM1
SCHEMBL2290076 0.72 TSHR (0.31) TDP1TSHRMAPTSMN1; SMN2
SCHEMBL22151404 0.72 TDP1 (0.46) TDP1TSHRCHRM2CHRM4CHRM1
SCHEMBL10782810 0.69 TSHR (0.50) TDP1TSHRCHRM2CHRM4CHRM1
SCHEMBL6138765 0.68 TDP1 (0.50) TDP1TSHRCHRM2CHRM4CHRM1
SCHEMBL704986 0.68 TSHR (0.39) TDP1TSHRCHRM2CHRM4CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624168-B2 Methods for making polyfunctional organosiloxanes and compositions containing same DOW SILICONES CORPORATION (US) 2026-05-12 US disclosed
US-20260118791-A1 TONER CANON KK (JP) 2026-04-30 US disclosed
EP-4086705-B1 TONER CANON KK (JP) 2026-03-25 EP disclosed
EP-4012501-B1 EXTERNAL ADDITIVE FOR TONER, TONER AND IMAGE FORMING APPARATUS CANON KK (JP) 2026-02-11 EP disclosed
EP-3654105-B1 PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS CANON KK (JP) 2026-01-28 EP disclosed
EP-4519346-B1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2026-01-14 EP disclosed
US-12497509-B2 Method for manufacturing a silicone elastomer article using a 3D printer ELKEM SILICONES FRANCE SAS (FR) 2025-12-16 US disclosed
US-12487539-B2 Fine particle, external additive for toners, and toner CANON KABUSHIKI KAISHA (JP) 2025-12-02 US disclosed
US-20250355380-A1 TWO-COMPONENT DEVELOPER CANON KK (JP) 2025-11-20 US disclosed
EP-3645607-B1 METHOD FOR HYDROSILYLATION OF ALIPHATICALLY UNSATURATED ALKOXYSILANES AND HYDROGEN TERMINATED ORGANOSILOXANE OLIGOMERS TO PREPARE ALKOXYSILYL TERMINATED POLYMERS USEFUL FOR FUNCTIONALIZING POLYORGANOSILOXANES USING AN IRIDIUM CATALYST DOW SILICONES CORP (US) 2025-11-05 EP disclosed
WO-2013009840-A1 LANTHANIDE COMPLEXES WITH IMIDAZOLE LIGANDS FOR CONDENSATION REACTIONS DOW CORNING CORPORATION (US) 2013-01-17 WO disclosed
WO-2013009836-A1 SAMARIUM CONTAINING COMPLEXES AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-01-17 WO disclosed
WO-2012134784-A1 COMPOSITIONS CONTAINING PHOSPHONATE CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS DOW CORNING CORPORATION (US) 2012-10-04 WO disclosed
WO-2012134786-A1 COMPOSITIONS CONTINING SULFONIC ACID CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS DOW CORNING CORPORATION (US) 2012-10-04 WO disclosed
WO-2012134788-A1 COMPOSITIONS CONTAINING PHOSPHATE CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS DOW CORNING CORPORATION (US) 2012-10-04 WO disclosed
WO-2012047312-A1 BIODEGRADABLE HYDROPHOBIC CELLULOSIC SUBSTRATES AND METHODS FOR THEIR PRODUCTION USING REACTIVE SILANES DOW CORNING CORPORATION (US) 2012-04-12 WO disclosed
US-8142856-B2 Preparing hydrolyzate containing polysiloxanes by hydrolyzing hydrolysable silane or hydrolysable silane mixture in presence of acid hydrolysis catalyst andcombining polysiloxane hydrolyzate with mineral and/or filler and optionally with water and/or a catalyst for condensation of the hydrolyzate DOW CORNING CORPORATION (US) 2012-03-27 US disclosed
US-20080286474-A1 Hydrophobing Minerals and Filler Materials DOW SILICONES CORPORATION 2008-11-20 US disclosed
EP-1904415-A2 HYDROPHOBING MINERALS AND FILLER MATERIALS Dow Corning Corporation (US) 2008-04-02 EP disclosed
WO-2007009935-A2 HYDROPHOBING MINERALS AND FILLER MATERIALS DOW CORNING CORPORATION (US) 2007-01-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260118791-A1 TONER MSR1, H1-2, TAAR1 TDP1 90/4885TSHR 165/4885CHRM2 23/4885
US-12624168-B2 Methods for making polyfunctional organosiloxanes and compositions containing same HAO2, H1-2, HRH2 TDP1 2802/4885TSHR 549/4885CHRM2 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.