SCHEMBL83904

SCHEMBL83904

c1ncc2ccsc2n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362763 1.00
SCHEMBL30155277 0.98 CHEK1 (0.41)
Bromide SCHEMBL10378261 0.98 CHEK1 (0.41)
Piperazine SCHEMBL798343 0.88 HTR2C (0.44)
SCHEMBL27748296 0.85 EGFR (0.40)
Acetamide SCHEMBL9933180 0.85 NPC1 (0.38)
SCHEMBL29991493 0.80
SCHEMBL35212535 0.77
SCHEMBL29952007 0.70 PIK3CG (0.39)
SCHEMBL27462264 0.70 EGFR (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1792 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325555-A1 Method of Treating Obesity with a Luteinizing Hormone Receptor Agonist ICAHN SCHOOL MED MOUNT SINAI (US) 2025-10-23 US claimed
EP-4536352-A2 METHOD OF TREATING OBESITY WITH A LUTEINIZING HORMONE RECEPTOR AGONIST Icahn School of Medicine at Mount Sinai (US) 2025-04-16 EP claimed
WO-2024245444-A1 OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-12-05 WO claimed
US-20240208968-A1 ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF DICE MOLECULES SV, INC. 2024-06-27 US claimed
EP-4304716-A1 ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF Dice Molecules Sv, Inc. (US) 2024-01-17 EP claimed
WO-2023239854-A2 METHOD OF TREATING OBESITY WITH A LUTEINIZING HORMONE RECEPTOR AGONIST ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2023-12-14 WO claimed
EP-4263539-A1 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE TREATMENT OF INFECTIOUS DISEASES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) 2023-10-25 EP claimed
US-11679111-B2 Fatty acid synthase inhibitors DUKE UNIVERSITY (US) 2023-06-20 US claimed
WO-2022192545-A1 ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF DICE MOLECULES SV, INC. (US) 2022-09-15 WO claimed
WO-2022129376-A1 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2022-06-23 WO claimed
WO-1997007119-A1 THIENOPYRIMIDINE DERIVATIVES, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-02-27 WO claimed
WO-1996035678-A1 ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE PHARMACIA & UPJOHN COMPANY (US) 1996-11-14 WO claimed
EP-0447891-B1 Thieno(2,3-d)pyrimidine derivatives BASF AG (DE) 1994-04-27 EP claimed
CN-1076697-A BIHETEROCYCLIC FUNGICIDAL COMPOUNDS SCHERING AGROCHEMICALS LTD (GB) 1993-09-29 CN claimed
WO-1993013664-A2 BIHETEROCYCLIC FUNGICIDAL COMPOUNDS SCHERING AGROCHEMICALS LIMITED (GB) 1993-07-22 WO claimed
EP-0452002-A2 Thienopyrimidine derivatives DOWELANCO (US) 1991-10-16 EP claimed
EP-0447891-A1 Thieno(2,3-d)pyrimidine derivatives BASF Aktiengesellschaft (DE) 1991-09-25 EP claimed
EP-0150469-B1 THIENO(2,3-D)PYRIMIDINE DERIVATIVES AND SALTS THEREOF MITSUBISHI KASEI CORPORATION (JP) 1988-06-15 EP claimed
US-4695568-A Thieno[2,3-d]pyrimidine derivatives and salts thereof MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1987-09-22 US claimed
EP-0150469-A1 Thieno(2,3-d)pyrimidine derivatives and salts thereof MITSUBISHI KASEI CORPORATION (JP) 1985-08-07 EP claimed