SCHEMBL29952007

SCHEMBL29952007

c1ncc2nc3sccc3nc2n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.39
EGFR P00533 3/20 0.33
CLK4 Q9HAZ1 2/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
KMT2A Q03164 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CHEK1 O14757 1/20 0.31
AURKA O14965 1/20 0.31
DAPK3 O43293 1/20 0.31
JAK2 O60674 1/20 0.31
MAP4K4 O95819 1/20 0.31
ABL1 P00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3292267 0.78 PIK3CG (0.47) PIK3CGEGFRCLK4ALDH1A1CYP1A2
SCHEMBL17865293 0.76 NTRK1 (0.37) CLK4KMT2AHSD17B10CHEK1AURKA
SCHEMBL19118755 0.73 PIK3CG (0.36) PIK3CGEGFR
SCHEMBL1378685 0.71 PIK3CG (0.46) PIK3CGEGFRALDH1A1CYP1A2CYP3A4
SCHEMBL30124132 0.71 EGFR (0.54) PIK3CGEGFRCLK4MEN1USP2
SCHEMBL35632 0.71 EGFR (0.54) PIK3CGEGFRCLK4MEN1USP2
SCHEMBL83904 0.70
SCHEMBL29362763 0.70
SCHEMBL30155277 0.69 CHEK1 (0.41) EGFRCLK4MEN1ALDH1A1KMT2A
SCHEMBL30611771 0.69 PIK3CG (0.41) PIK3CGEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702652-B2 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION A/S (DK) 2023-07-18 US disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed