Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839053 | 1.00 | KMT2A (0.44) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL839114 | 0.88 | KMT2A (0.49) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL839115 | 0.88 | KMT2A (0.49) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL839804 | 0.88 | KMT2A (0.49) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL839742 | 0.83 | GAA (0.49) | KMT2AMAPTMEN1SMN1; SMN2NPSR1 | |
| SCHEMBL839239 | 0.83 | GAA (0.49) | KMT2AMAPTMEN1SMN1; SMN2NPSR1 | |
| SCHEMBL839240 | 0.83 | GAA (0.49) | KMT2AMAPTMEN1SMN1; SMN2NPSR1 | |
| SCHEMBL840335 | 0.83 | KMT2A (0.49) | KMT2AMAPTMEN1SMN1; SMN2HTT | |
| SCHEMBL840334 | 0.83 | KMT2A (0.49) | KMT2AMAPTMEN1SMN1; SMN2HTT | |
| SCHEMBL838465 | 0.82 | RAB9A (0.49) | KMT2AMAPTMEN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143052-B2 | Process for preparing optically active (S or R)-α amino acid and (R or S)-α amino acid ester in one phase organic reaction medium | UBE INDUSTRIES, LTD. (JP) | 2012-03-27 | — | — | US | disclosed |