SCHEMBL8390946

SCHEMBL8390946

O=P(O)(O)CCC(F)c1nc[nH]n1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 4/20 0.33
PGK2 P07205 4/20 0.33
ENPEP Q07075 1/20 0.31
HPRT1 P00492 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8387758 0.81 ENPEP (0.35) ENPEPHPRT1
SCHEMBL8385622 0.80 ENPEP (0.31) ENPEPHPRT1
SCHEMBL8388050 0.80 ENPEP (0.38) ENPEPHPRT1
SCHEMBL8388023 0.80 ENPEP (0.31) ENPEPHPRT1
SCHEMBL8390494 0.80 ENPEP (0.34) ENPEPHPRT1
SCHEMBL8385641 0.80 ENPEP (0.31) ENPEPHPRT1
SCHEMBL8389806 0.78 S1PR1 (0.31) HPRT1
SCHEMBL8386189 0.78 ENPEP (0.33) ENPEP
SCHEMBL9000123 0.78 HPRT1 (0.34) ENPEPHPRT1
SCHEMBL8390021 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5922644-A POSTEMERGENCE HERBICIDES EFFECTIVE AGAINST A BROAD RANGE OF WEED SPECIES; MAY BE USED AS SELECTIVE HERBICIDES IN SOYA, SUGAR BEET, AND OIL-SEED RAPE CROPS ZENECA LIMITED (GB) 1999-07-13 US disclosed
EP-0625873-B1 PHOSPHONIC ACID DERIVATIVES CONTAINING A TRIAZOLE RING AS HERBICIDES ZENECA LTD (GB) 1997-11-05 EP disclosed
US-5393732-A Triazole phosphoric acid derivatives and their use as herbicides ZENECA LIMITED (GB) 1995-02-28 US disclosed
EP-0625873-A1 PHOSPHONIC ACID DERIVATIVES CONTAINING A TRIAZOLE RING AS HERBICIDES ZENECA LIMITED (GB) 1994-11-30 EP disclosed
WO-1993015610-A1 PHOSPHONIC ACID DERIVATIVES CONTAINING A TRIAZOLE RING AS HERBICIDES ZENECA LIMITED (GB) 1993-08-19 WO disclosed